1. Gene
  2. HMGB4 - high mobility group box 4 Gene

HMGB4 - high mobility group box 4 Gene

中文名称:高机动性组框 4

种属: Homo sapiens

同用名: dJ1007G16.5

基因 ID: 127540 | 基因类型: protein coding

关于 HMGB4

Cytogenetic location: 1p35.1 Genomic coordinates (GRCh38): 1:33,860,475-33,864,791 (from NCBI)

This gene has 5 transcripts (splice variants), 255 orthologues and 20 paralogues. Restricted expression toward testis (RPKM 70.9).

功能概要

预测可启用 DNA 结合活性、弯曲。预计参与 RNA 聚合酶 II 的转录调控。位于核内。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable DNA binding activity, bending. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

HMGB4 基因产物(3)

mRNA Protein Name
NM_001352984.2 NP_001339913.1 high mobility group protein B4 isoform 2
NM_001379301.1 NP_001366230.1 high mobility group protein B4 isoform 1
NM_145205.6 NP_660206.2 high mobility group protein B4 isoform 1

HMGB4 蛋白结构

HMG_box_2

HMG_box_2: HMG-box domain (8 - 78)

HMG_box

HMG_box: HMG (high mobility group) box (93 - 161)

  • 0
  • 100
  • 186 a.a.
蛋白主名 其他名称

high mobility group protein B4

HMG2 like

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus HMGB4 RGD RGD:1596426
Bos taurus HMGB4 VGNC VGNC:29876
Canis familiaris HMGB4 VGNC VGNC:41711
Felis catus HMGB4 VGNC VGNC:82378
Macaca mulatta HMGB4 VGNC VGNC:73437
Mus musculus HMGB4 MGD MGI:1916567