2. Gene
  3. Ncan - neurocan Gene

Ncan - neurocan Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Cspg3; Tgfbit; Cspg3-rs; C230035B04

基因 ID: 13004 | 基因类型: protein coding

关于 Ncan

功能概要

Predicted to enable calcium ion binding activity; carbohydrate binding activity; and hyaluronic acid binding activity. Acts upstream of or within regulation of synapse structural plasticity. Predicted to be located in perineuronal net. Predicted to be active in extracellular matrix. Is expressed in central nervous system; dorsal root ganglion; neural retina; olfactory system; and trigeminal nerve. Orthologous to human NCAN (neurocan). [provided by Alliance of Genome Resources, Apr 2022]

Ncan 基因产物(1)

mRNA Protein Name
NM_007789.3 NP_031815.2 neurocan core protein precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
11486035 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
11486035 MGI
involved in regulation of postsynapse organization EXP
EXP: 通过实验结果推断
30356641 MGI
involved in regulation of postsynapse organization IDA
IDA: 通过直接分析推断
30356641 MGI
acts upstream of or within regulation of synapse structural plasticity IMP
IMP: 通过突变表型推断
11486035 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
29670169 MGI
is active in glutamatergic synapse EXP
EXP: 通过实验结果推断
30356641 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
11486035 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
11486035 MGI
is active in perisynaptic extracellular matrix IDA
IDA: 通过直接分析推断
29670169 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neurocan core protein

TGFbeta-induced transcript, brain

chondroitin sulfate proteoglycan 3, related sequence

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09065 NCAN Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19622 Ncan Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26117 Ncan Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ncan NCBI NCBI:1463
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