1. Gene
  2. Epha8 - Eph receptor A8 Gene

Epha8 - Eph receptor A8 Gene

种属: Mus musculus

同用名: Eek; Hek3; mKIAA1459

基因 ID: 13842 | 基因类型: protein coding

关于 Epha8

功能概要

Enables GPI-linked Ephrin Receptor activity and growth factor binding activity. Involved in several processes, including Ephrin Receptor signaling pathway; neuron development; and positive regulation of phosphatidylinositol 3-kinase activity. Acts upstream of or within cellular response to follicle-stimulating hormone stimulus. Located in neuron projection. Is integral component of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human EphA8 (EPH receptor A8). [provided by Alliance of Genome Resources, Apr 2022]

Epha8 基因产物(1)

mRNA Protein Name
NM_007939.2 NP_031965.2 ephrin type-A receptor 8 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables GPI-linked ephrin receptor activity IDA
IDA: 通过直接分析推断
9053851 MGI
enables ephrin receptor activity IDA
IDA: 通过直接分析推断
11416136 MGI
enables growth factor binding IPI
IPI: 通过物理相互作用推断
22568954 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9053851 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in axon guidance IMP
IMP: 通过突变表型推断
9214628 MGI
acts upstream of or within cellular response to follicle-stimulating hormone stimulus IDA
IDA: 通过直接分析推断
23242526 MGI
involved in ephrin receptor signaling pathway IDA
IDA: 通过直接分析推断
9053851 MGI
involved in neuron projection development IDA
IDA: 通过直接分析推断
15782114 MGI
involved in neuron remodeling IDA
IDA: 通过直接分析推断
17875921 MGI
involved in positive regulation of MAPK cascade IDA
IDA: 通过直接分析推断
15782114 MGI
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
IDA: 通过直接分析推断
11416136 MGI
involved in protein autophosphorylation IDA
IDA: 通过直接分析推断
10498895 MGI
involved in regulation of cell adhesion IDA
IDA: 通过直接分析推断
10498895 MGI
involved in regulation of cell adhesion mediated by integrin IDA
IDA: 通过直接分析推断
11416136 MGI
involved in substrate-dependent cell migration IDA
IDA: 通过直接分析推断
17875921 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in neuron projection IDA
IDA: 通过直接分析推断
17875921 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
9053851 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ephrin type-A receptor 8

EPH- and ELK-related kinase

Ephrin type-A receptor 8 precursor (Tyrosine-protein kinase receptor EEK) (EPH-and ELK-related kinase)

tyrosine-protein kinase receptor EEK

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Epha8 NCBI NCBI:2046