2. Gene
  3. Fshr - follicle stimulating hormone receptor Gene

Fshr - follicle stimulating hormone receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 14309 | 基因类型: protein coding

关于 Fshr

功能概要

Enables follicle-stimulating hormone receptor activity. Acts upstream of or within several processes, including G protein-coupled receptor signaling pathway; gonad development; and regulation of signal transduction. Located in cell surface. Is expressed in early conceptus and gonad. Human ortholog(s) of this gene implicated in 46 XX gonadal dysgenesis; ovarian dysgenesis 1; and ovarian hyperstimulation syndrome. Orthologous to human FSHR (follicle stimulating hormone receptor). [provided by Alliance of Genome Resources, Apr 2022]

Fshr 基因产物(1)

mRNA Protein Name
NM_013523.3 NP_038551.3 follicle-stimulating hormone receptor precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables follicle-stimulating hormone receptor activity IDA
IDA: 通过直接分析推断
9206032 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Sertoli cell development IMP
IMP: 通过突变表型推断
14998910 MGI
acts upstream of or within Sertoli cell proliferation IMP
IMP: 通过突变表型推断
11466221 MGI
acts upstream of or within adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
16630814 MGI
acts upstream of or within adenylate cyclase-modulating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
10330114 MGI
acts upstream of or within basement membrane organization IMP
IMP: 通过突变表型推断
9811848 MGI
acts upstream of or within follicle-stimulating hormone signaling pathway IDA
IDA: 通过直接分析推断
10330114 MGI
acts upstream of or within intracellular water homeostasis IMP
IMP: 通过突变表型推断
14998910 MGI
acts upstream of or within locomotory behavior IMP
IMP: 通过突变表型推断
14502087 MGI
acts upstream of or within negative regulation of bone resorption IMP
IMP: 通过突变表型推断
11089565 MGI
acts upstream of or within neuron projection development IMP
IMP: 通过突变表型推断
12204217 MGI
acts upstream of or within ovarian follicle development IMP
IMP: 通过突变表型推断
9811848 MGI
acts upstream of or within ovulation cycle process IMP
IMP: 通过突变表型推断
11089565 MGI
acts upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
10330114 MGI
acts upstream of or within positive regulation of intracellular estrogen receptor signaling pathway IMP
IMP: 通过突变表型推断
11089565 MGI
acts upstream of or within primary ovarian follicle growth IMP
IMP: 通过突变表型推断
12801993 MGI
acts upstream of or within regulation of MAPK cascade IMP
IMP: 通过突变表型推断
12204217 MGI
acts upstream of or within regulation of acetylcholine metabolic process IGI
IGI: 通过遗传相互作用推断
12204217 MGI
acts upstream of or within regulation of chromosome organization IMP
IMP: 通过突变表型推断
14680821 MGI
acts upstream of or within regulation of hormone metabolic process IMP
IMP: 通过突变表型推断
12204217 MGI
acts upstream of or within regulation of intracellular estrogen receptor signaling pathway IMP
IMP: 通过突变表型推断
18063689 MGI
acts upstream of or within regulation of osteoclast differentiation IMP
IMP: 通过突变表型推断
16630814 MGI
acts upstream of or within regulation of platelet-derived growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
16344272 MGI
acts upstream of or within regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
12204217 MGI
acts upstream of or within regulation of systemic arterial blood pressure IMP
IMP: 通过突变表型推断
18599597 MGI
acts upstream of or within sperm DNA condensation IMP
IMP: 通过突变表型推断
10775161 MGI
acts upstream of or within spermatid development IMP
IMP: 通过突变表型推断
11466221 MGI
acts upstream of or within spermatogenesis IMP
IMP: 通过突变表型推断
9811848 MGI
acts upstream of or within uterus development IMP
IMP: 通过突变表型推断
10803590 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
16630814 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

follicle-stimulating hormone receptor

follitropin receptor

相关产品

Pre-clinical Phase
生物活性分子 (11)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-12381 ML224 Antagonist 99.18% 否
HY-P4190 Fsh receptor-binding inhibitor fragment(bi-10) Antagonist 99.77% 否
HY-P3343A hFSH-β-(33-53) (TFA) Agonist 99.16% 否
HY-150210 FSHR agonist 1 Agonist 99.45% 否
HY-164764 ADX61623 Inhibitor 98.84% 否
HY-160857 TOP5668 Agonist 98.07% 否
HY-160856 TOP5300 Agonist / 否
HY-P10780 RFRP-3 (mouse) / 否
HY-RS05124 FSHR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16988 Fshr Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23431 Fshr Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fshr NCBI NCBI:2492
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