2. Gene
  3. Gbp2 - guanylate binding protein 2 Gene

Gbp2 - guanylate binding protein 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 14469 | 基因类型: protein coding

关于 Gbp2

功能概要

Predicted to enable several functions, including HSP90 protein binding activity; cytoskeletal protein binding activity; and guanyl ribonucleotide binding activity. Acts upstream of or within several processes, including cellular response to interferon-beta; cellular response to lipopolysaccharide; and defense response to Other organism. Located in cytoplasmic vesicle and symbiont-containing vacuole membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and sensory organ. Orthologous to several human genes including GBP2 (guanylate binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Gbp2 基因产物(1)

mRNA Protein Name
NM_010260.1 NP_034390.1 guanylate-binding protein 2
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in activation of innate immune response IMP
IMP: 通过突变表型推断
24739961 MGI
acts upstream of or within adhesion of symbiont to host IDA
IDA: 通过直接分析推断
18025219 MGI
acts upstream of or within cellular response to interferon-beta IDA
IDA: 通过直接分析推断
19158679 MGI
involved in cellular response to interferon-beta IDA
IDA: 通过直接分析推断
18025219 MGI
acts upstream of or within cellular response to lipopolysaccharide IDA
IDA: 通过直接分析推断
18025219 MGI
involved in cellular response to lipopolysaccharide IMP
IMP: 通过突变表型推断
24715728 MGI
acts upstream of or within cellular response to type II interferon IDA
IDA: 通过直接分析推断
18025219 MGI
involved in cytolysis in another organism IDA
IDA: 通过直接分析推断
25774715 MGI
involved in cytolysis in another organism IMP
IMP: 通过突变表型推断
24715728 MGI
acts upstream of or within defense response to Gram-positive bacterium IDA
IDA: 通过直接分析推断
18025219 MGI
involved in defense response to bacterium IDA
IDA: 通过直接分析推断
25774715 MGI
involved in defense response to bacterium IMP
IMP: 通过突变表型推断
24715728 MGI
acts upstream of or within defense response to protozoan IDA
IDA: 通过直接分析推断
18025219 MGI
involved in positive regulation of AIM2 inflammasome complex assembly IDA
IDA: 通过直接分析推断
25774715 MGI
involved in positive regulation of pyroptotic inflammatory response IDA
IDA: 通过直接分析推断
25774715 MGI
involved in positive regulation of pyroptotic inflammatory response IMP
IMP: 通过突变表型推断
24715728 MGI
involved in protein targeting IDA
IDA: 通过直接分析推断
27693356 MGI
acts upstream of or within response to bacterium IEP
IEP: 通过表达模式推断
23012479 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasmic vesicle IDA
IDA: 通过直接分析推断
18025219 MGI
is active in symbiont cell surface IDA
IDA: 通过直接分析推断
27693356 MGI
located in symbiont-containing vacuole membrane IDA
IDA: 通过直接分析推断
18025219 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

guanylate-binding protein 2

GBP-2

GTP-binding protein 2

guanine nucleotide-binding protein 2

guanylate nucleotide binding protein 2

guanylate-binding protein 1

interferon-induced guanylate-binding protein 2

mGBP-2

mGBP2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05308 GBP2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17953 Gbp2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24424 Gbp2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gbp2 NCBI NCBI:2634
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