1. Gene
  2. GBP2 - guanylate binding protein 2 Gene

GBP2 - guanylate binding protein 2 Gene

中文名称:鸟苷酸结合蛋白 2

种属: Homo sapiens

基因 ID: 2634 | 基因类型: protein coding

关于 GBP2

Cytogenetic location: 1p22.2 Genomic coordinates (GRCh38): 1:89,106,132-89,126,114 (from NCBI)

This gene has 4 transcripts (splice variants), 144 orthologues and 10 paralogues. Ubiquitous expression in appendix (RPKM 36.9), urinary bladder (RPKM 31.7) and 24 other tissues.

功能概要

该基因属于鸟嘌呤结合蛋白 (GBP) 家族,其中包括可与鸟嘌呤核苷酸 (GMP、GDP 和 GTP) 结合的干扰素诱导蛋白。编码的蛋白质是一种 GTP 酶,可水解 GTP,主要是生成 GDP。该蛋白可能作为鳞状细胞癌的标志物发挥作用。[RefSeq 提供,2013 年 7 月]

This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas. [provided by RefSeq, Jul 2013]

GBP2 基因产物(1)

mRNA Protein Name
NM_004120.5 NP_004111.2 guanylate-binding protein 2

GBP2 蛋白结构

GBP

GBP: Guanylate-binding protein, N-terminal domain (19 - 280)

GBP_C

GBP_C: Guanylate-binding protein, C-terminal domain (282 - 578)

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  • 591 a.a.
蛋白主名 其他名称

guanylate-binding protein 2

GTP-binding protein 2

重组 GBP2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P75787 GBP2 Protein, Human (HEK293, His) AAH73163.1 (M1-C588) ≥95%

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus GBP2 RGD RGD:621810
Mus musculus GBP2 NCBI
Others GBP2 NCBI