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  2. Ifnar2 - interferon (alpha and beta) receptor 2 Gene

Ifnar2 - interferon (alpha and beta) receptor 2 Gene

中文名称:干扰素 (α 和 β) 受体 2

种属: Mus musculus

同用名: Ifnar-2

基因 ID: 15976 | 基因类型: protein coding

关于 Ifnar2

Chromosome 16: 91,169,671-91,202,477 forward strand.GRCm39:CM001009.3

This gene has 5 transcripts (splice variants), 303 orthologues, 11 paralogues and is associated with 17 phenotypes. Ubiquitous expression in adrenal adult (RPKM 31.7), lung adult (RPKM 17.) and 27 other tissues.

功能概要

该基因编码的蛋白可启动 I 型干扰素受体活性。通过 RNA 聚合酶 II 作用于细胞群增殖和转录调节的上游或内部。位于细胞外空间。以多种结构表达,包括泌尿生殖系统;直觉;淋巴系统;肝;和神经系统。该基因与乙型肝炎和免疫缺陷 45 相关的人类直向同源基因。与人类 IFNAR2(干扰素 α 和 β 受体亚基 2)直向同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables type I interferon receptor activity. Acts upstream of or within cell population proliferation and regulation of transcription by RNA polymerase II. Located in extracellular space. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system; liver; and nervous system. Human ortholog(s) of this gene implicated in hepatitis B and immunodeficiency 45. Orthologous to human IFNAR2 (interferon alpha and beta receptor subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Ifnar2 基因产物(3)

mRNA Protein Name
NM_001347258.1 NP_001334187.1 interferon alpha/beta receptor 2 isoform c precursor
NM_001110498.1 NP_001103968.1 interferon alpha/beta receptor 2 isoform b precursor
NM_010509.2 NP_034639.2 interferon alpha/beta receptor 2 isoform a precursor

Ifnar2 蛋白结构

FN3

FN3: cl21522 (15 - 106)

Interfer-bind

Interfer-bind: pfam09294 (131 - 227)

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  • 513 a.a.
蛋白主名 其他名称

interferon alpha/beta receptor 2

IFN-R-2

IFN-alpha/beta receptor 2

interferon receptor 2a'

interferon receptor 2c

type I interferon alpha/beta receptor 2a

type I interferon receptor 2

重组 Ifnar2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P78772 IFN-alpha/beta R2 Protein, Mouse (HEK293, His) O35664-1 (S22-A242) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ifnar2 NCBI NCBI:3455
Macaca fascicularis Ifnar2 NCBI NCBI:102140083