2. Gene
  3. Asic3 - acid-sensing (proton-gated) ion channel 3 Gene

Asic3 - acid-sensing (proton-gated) ion channel 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Accn3; TNAC1; DRASIC; SLNAC1

基因 ID: 171209 | 基因类型: protein coding

关于 Asic3

功能概要

Enables cation channel activity and enterobactin transmembrane transporter activity. Acts upstream of or within several processes, including detection of stimulus involved in sensory perception of pain; response to acidic pH; and response to heat. Is integral component of plasma membrane. Is expressed in cranial ganglion; dorsal root ganglion; and pectoral girdle and thoracic body wall muscle. Orthologous to human ASIC3 (acid sensing ion channel subunit 3). [provided by Alliance of Genome Resources, Apr 2022]

Asic3 基因产物(2)

mRNA Protein Name
NM_001310474.1 NP_001297403.1 acid-sensing ion channel 3 isoform 2
NM_183000.2 NP_892045.2 acid-sensing ion channel 3 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables enterobactin transmembrane transporter activity IMP
IMP: 通过突变表型推断
19590043 MGI
enables monoatomic cation channel activity IDA
IDA: 通过直接分析推断
11854527 MGI
enables monoatomic cation channel activity IMP
IMP: 通过突变表型推断
11854527 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within detection of chemical stimulus involved in sensory perception IMP
IMP: 通过突变表型推断
11754838 MGI
acts upstream of or within detection of chemical stimulus involved in sensory perception of pain IMP
IMP: 通过突变表型推断
11754838 MGI
acts upstream of or within detection of mechanical stimulus involved in sensory perception IMP
IMP: 通过突变表型推断
11754838 MGI
acts upstream of or within detection of mechanical stimulus involved in sensory perception of pain IMP
IMP: 通过突变表型推断
11754838 MGI
acts upstream of or within detection of temperature stimulus involved in sensory perception IMP
IMP: 通过突变表型推断
11754838 MGI
acts upstream of or within detection of temperature stimulus involved in sensory perception of pain IMP
IMP: 通过突变表型推断
12060708 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: 通过突变表型推断
19590043 MGI
acts upstream of or within monoatomic cation transport IDA
IDA: 通过直接分析推断
11854527 MGI
acts upstream of or within monoatomic cation transport IMP
IMP: 通过突变表型推断
11854527 MGI
acts upstream of or within monoatomic ion transmembrane transport IMP
IMP: 通过突变表型推断
19590043 MGI
acts upstream of or within response to acidic pH IDA
IDA: 通过直接分析推断
11854527 MGI
acts upstream of or within response to acidic pH IMP
IMP: 通过突变表型推断
11754838 MGI
acts upstream of or within response to heat IMP
IMP: 通过突变表型推断
11754838 MGI
acts upstream of or within response to mechanical stimulus IMP
IMP: 通过突变表型推断
11754838 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
11854527 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

acid-sensing ion channel 3

amiloride-sensitive cation channel 3

dorsal root ASIC

相关产品

Pre-clinical Phase
生物活性分子 (14)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-107757 GMQ hydrochloride Activator 99.86% 否
HY-122135 A-317567 Inhibitor 98.45% 否
HY-131879 NS383 99.83% 否
HY-D2868 DAPI Inhibitor 98.01% 否
HY-P1346A APETx2 TFA Inhibitor 98.54% 否
HY-P1441A Mambalgin 1 TFA Inhibitor 95.72% 否
HY-P1346 APETx2 Inhibitor / 否
HY-100939 4-Chlorophenylguanidine hydrochloride Agonist 99.07% 否
HY-155017 6-Iodoamiloride Inhibitor / 否
HY-P1249 Neuropeptide SF(mouse,rat) Agonist / 否
HY-P1249A Neuropeptide SF(mouse,rat) TFA Agonist / 否
HY-RS01091 ASIC3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17225 Asic3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23678 Asic3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Asic3 NCBI NCBI:9311
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