2. Gene
  3. DLX2 - distal-less homeobox 2 Gene

DLX2 - distal-less homeobox 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：无远端同源框 2

种属: Homo sapiens

同用名: TES1; TES-1

基因 ID: 1746 | 基因类型: protein coding

关于 DLX2

Cytogenetic location: 2q31.1 Genomic coordinates (GRCh38): 2:172,099,438-172,102,900 (from NCBI)

This gene has 2 transcripts (splice variants), 227 orthologues and 9 paralogues. Low expression observed in reference dataset.

功能概要

许多脊椎动物含有同源框的基因已根据它们与果蝇发育基因的序列相似性得到鉴定。 Dlx 基因家族的成员包含一个与 Distal-less (Dll) 基因相关的同源盒，Dll 是一种在发育中的果蝇的头部和四肢中表达的基因。 Distal-less (Dlx) 基因家族包含至少 6 个不同的成员，DLX1-DLX6。 DLX 蛋白被假定在前脑和颅面发育中发挥作用。该基因与 2 号染色体长臂上的基因家族的另一个成员呈尾对尾配置。[RefSeq 提供，2008 年 7 月]

Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2. [provided by RefSeq, Jul 2008]

DLX2 基因产物(1)

mRNA Protein Name
NM_004405.4 NP_004396.1 homeobox protein DLX-2

DLX2 蛋白结构

DLL_N

DLL_N: Homeobox protein distal-less-like N terminal (51 - 132)

Homeobox

Homeobox: Homeobox domain (153 - 209)

  • 0
  • 100
  • 200
  • 300
  • 328 a.a.
蛋白主名 其他名称

homeobox protein DLX-2

distal-less homeo box 2

关联疾病

疾病名称 别名
Tooth Agenesis

Oligodontia

Hypodontia

Selective Tooth Agenesis

Tooth Agenesis, Selective

Familial Tooth Agenesis

Anodontia

Congenital Absence Of One Tooth
Trichodentoosseous Syndrome

Tricho-Dento-Osseous Syndrome

Tdo Syndrome

Trichodontoosseous Syndrome

TDO

Enamel Hypoplasia And Hypocalcification With Associated Strikingly Curly Hair
Syngnathia

Cleft Palate-Lateral Synechia Syndrome

Cpls Syndrome

Cleft Palate Lateral Synechia Syndrome
Ectodermal Dysplasia

Congenital Ectodermal Defect

Congenital Ectodermal Dysplasia

Ectodermal Dysplasia Syndrome

Dysplasia, Ectodermal
Split Hand-Foot Malformation

Ectrodactyly

Split-Hand/Foot Malformation

Lobster-Claw Deformity

Split-Hand Deformity

Split Hand Foot Malformation

Shfm

Split Hand Foot Deformity

Split Hand Foot Deformity 1
Axenfeld-Rieger Syndrome

Axenfeld Syndrome

Rieger Syndrome

Rieger Anomaly

Axenfeld Anomaly

Anomaly, Rieger'S

Hagedoom Syndrome

Rgs - Rieger Syndrome

Rieger'S Anomaly

Goniodysgenesis Hypodontia

Iridogoniodysgenesis With Somatic Anomalies

Ars

Axenfeld And Rieger Anomaly

Axra

Axrs

Rieger Eye Malformation Sequence
Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic
Orofacial Cleft

Cleft, Orofacial
Congenital Nervous System Abnormality

Congenital Neurologic Anomaly

Congenital Nervous System Disorder
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03813 DLX2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus DLX2 MGD MGI:94902
Rattus norvegicus DLX2 RGD RGD:1304853
Canis familiaris DLX2 VGNC VGNC:39990
Bos taurus DLX2 VGNC VGNC:28099
Macaca mulatta DLX2 VGNC VGNC:104522
Felis catus DLX2 VGNC VGNC:80181
Others DLX2 NCBI
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