2. Gene
  3. Nedd8 - neural precursor cell expressed, developmentally down-regulated gene 8 Gene

Nedd8 - neural precursor cell expressed, developmentally down-regulated gene 8 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Rub1; NEDD-8

基因 ID: 18002 | 基因类型: protein coding

关于 Nedd8

功能概要

Predicted to enable protein tag and ubiquitin protein Ligase binding activity. Acts upstream of or within protein localization and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; peripheral nervous system ganglion; and sensory organ. Orthologous to human NEDD8 (NEDD8 ubiquitin like modifier). [provided by Alliance of Genome Resources, Apr 2022]

Nedd8 基因产物(1)

mRNA Protein Name
NM_008683.4 NP_032709.1 NEDD8
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12215427 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within protein localization IDA
IDA: 通过直接分析推断
12215427 MGI
involved in regulation of postsynapse assembly EXP
EXP: 通过实验结果推断
25581363 MGI
involved in regulation of postsynapse assembly IDA
IDA: 通过直接分析推断
25581363 MGI
involved in regulation of postsynapse assembly IMP
IMP: 通过突变表型推断
25581363 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12215427 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse EXP
EXP: 通过实验结果推断
25581363 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
25581363 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
25581363 MGI
located in nucleus IDA
IDA: 通过直接分析推断
12215427 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

NEDD8

neddylin

neural precursor cell expressed developmentally down-regulated protein 8

ubiquitin-like protein Nedd8

相关产品

Clinical Phase
生物活性分子 (4)
目录号 产品名 作用方式
纯度 Phase
HY-70062 Pevonedistat 99.98% Phase 3
HY-10484 Pevonedistat hydrochloride 99.19% Phase 3
HY-128586 TAS4464 Inhibitor 99.21% Phase 1
HY-128586A TAS4464 hydrochloride Inhibitor 98.91% Phase 1
Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-108702 ML-792 Inhibitor 99.76% 否
HY-101790A ZM223 hydrochloride Inhibitor 98.93% 否
HY-115537 NAE-IN-M22 Activator 99.94% 否
HY-101790 ZM223 Inhibitor / 否
HY-163105 Tubulin/NEDDylation-IN-1 Inhibitor 98.03% 否
HY-159601 CSN5-IN-1 Inhibitor / 否
HY-RS09181 NEDD8 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17081 Nedd8 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23525 Nedd8 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nedd8 NCBI NCBI:4738
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