2. Gene
  3. Pck1 - phosphoenolpyruvate carboxykinase 1, cytosolic Gene

Pck1 - phosphoenolpyruvate carboxykinase 1, cytosolic Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: PEPCK; Pck-1; PEPCK-C

基因 ID: 18534 | 基因类型: protein coding

关于 Pck1

功能概要

Enables phosphoenolpyruvate carboxykinase (GTP) activity. Involved in oxaloacetate metabolic process and positive regulation of memory T cell differentiation. Acts upstream of or within several processes, including cellular response to potassium ion starvation; gluconeogenesis; and glycerol biosynthetic process from pyruvate. Located in cytosol. Is expressed in several structures, including alimentary system; brown fat; liver; and urinary system. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Orthologous to human PCK1 (phosphoenolpyruvate carboxykinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Pck1 基因产物(1)

mRNA Protein Name
NM_011044.3 NP_035174.1 phosphoenolpyruvate carboxykinase, cytosolic [GTP]
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables phosphoenolpyruvate carboxykinase (GTP) activity IMP
IMP: 通过突变表型推断
10938127 MGI
enables phosphoenolpyruvate carboxykinase activity IMP
IMP: 通过突变表型推断
11792850 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to potassium ion starvation IDA
IDA: 通过直接分析推断
19458124 MGI
acts upstream of or within gluconeogenesis IDA
IDA: 通过直接分析推断
11916968 MGI
involved in gluconeogenesis IDA
IDA: 通过直接分析推断
19643083 MGI
involved in gluconeogenesis IMP
IMP: 通过突变表型推断
10938127 MGI
involved in glyceraldehyde-3-phosphate biosynthetic process IMP
IMP: 通过突变表型推断
11792850 MGI
acts upstream of or within glycerol biosynthetic process from pyruvate IMP
IMP: 通过突变表型推断
11792850 MGI
acts upstream of or within lipid metabolic process IMP
IMP: 通过突变表型推断
11792850 MGI
involved in oxaloacetate metabolic process IMP
IMP: 通过突变表型推断
29230018 MGI
involved in positive regulation of memory T cell differentiation IMP
IMP: 通过突变表型推断
29230018 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
19458124 MGI
acts upstream of or within response to bacterium IEP
IEP: 通过表达模式推断
23012479 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cytosol IDA
IDA: 通过直接分析推断
19458124 MGI
located in cytosol IDA
IDA: 通过直接分析推断
19458124 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

phosphoenolpyruvate carboxykinase, cytosolic [GTP]

phosphoenolpyruvate carboxykinase, cytosolic

phosphoenolpyruvate carboxylase

serine-protein kinase PCK1

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-116688 2-Hydroxy-4-(methylthio)butyric acid 88.0% 否
HY-175266 MI1013 / 否
HY-RS10152 PCK1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17590 Pck1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24050 Pck1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pck1 NCBI NCBI:5105
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