2. Gene
  3. Pstpip1 - proline-serine-threonine phosphatase-interacting protein 1 Gene

Pstpip1 - proline-serine-threonine phosphatase-interacting protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: def-2; CD2BP1

基因 ID: 19200 | 基因类型: protein coding

关于 Pstpip1

功能概要

Enables actin binding activity and protein Phosphatase binding activity. Predicted to be involved in actin filament polymerization. Predicted to act upstream of or within several processes, including endocytosis; inflammatory response; and innate immune response. Located in actomyosin contractile ring; cleavage furrow; and stress fiber. Is expressed in several structures, including genitourinary system; lung; musculature; pancreas; and spleen. Human ortholog(s) of this gene implicated in PAPA syndrome. Orthologous to human PSTPIP1 (proline-serine-threonine Phosphatase interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Pstpip1 基因产物(13)

mRNA Protein Name
NM_001409150.1 NP_001396079.1 proline-serine-threonine phosphatase-interacting protein 1 isoform 2
NM_001409151.1 NP_001396080.1 proline-serine-threonine phosphatase-interacting protein 1 isoform 3
NM_001409152.1 NP_001396081.1 proline-serine-threonine phosphatase-interacting protein 1 isoform 4
NM_001409153.1 NP_001396082.1 proline-serine-threonine phosphatase-interacting protein 1 isoform 5
NM_001409154.1 NP_001396083.1 proline-serine-threonine phosphatase-interacting protein 1 isoform 6
NM_001409155.1 NP_001396084.1 proline-serine-threonine phosphatase-interacting protein 1 isoform 7
NM_001409156.1 NP_001396085.1 proline-serine-threonine phosphatase-interacting protein 1 isoform 8
NM_001409157.1 NP_001396086.1 proline-serine-threonine phosphatase-interacting protein 1 isoform 9
NM_001409158.1 NP_001396087.1 proline-serine-threonine phosphatase-interacting protein 1 isoform 10
NM_001409159.1 NP_001396088.1 proline-serine-threonine phosphatase-interacting protein 1 isoform 11
NM_001409160.1 NP_001396089.1 proline-serine-threonine phosphatase-interacting protein 1 isoform 11
NM_001409161.1 NP_001396090.1 proline-serine-threonine phosphatase-interacting protein 1 isoform 11
NM_011193.3 NP_035323.2 proline-serine-threonine phosphatase-interacting protein 1 isoform 1
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin binding IDA
IDA: 通过直接分析推断
9265651 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9265651 MGI
enables protein phosphatase binding IDA
IDA: 通过直接分析推断
9265651 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actomyosin contractile ring IDA
IDA: 通过直接分析推断
9265651 MGI
located in cleavage furrow IDA
IDA: 通过直接分析推断
9265651 MGI
located in stress fiber IDA
IDA: 通过直接分析推断
9265651 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

proline-serine-threonine phosphatase-interacting protein 1

PEST phosphatase-interacting protein 1

Pstpip1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Pstpip1 P97814 Ptpn12 Mus musculus P35831
Anti Bait CoIP
16204241
种属内
Pstpip1 P97814 Ptpn12 Mus musculus P35831
Anti Bait CoIP
11711533
种属内
Pstpip1 P97814 Ptpn12 Mus musculus P35831
IF
11711533
种属内
Pstpip1 P97814 Ptpn18 Mus musculus Q61152
Pull Down
9804817
种属内
Pstpip1 P97814 Abl1 Mus musculus P00520
Anti Tag CoIP
11163214
种属内
Pstpip1 P97814 Abl1 Mus musculus P00520
Anti Bait CoIP
11163214
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11345 PSTPIP1 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pstpip1 NCBI NCBI:9051
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