2. Gene
  3. Ptpra - protein tyrosine phosphatase, receptor type, A Gene

Ptpra - protein tyrosine phosphatase, receptor type, A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ptpa; Rptra; Ptpalpha; Rptpalpha; Rptralpha

基因 ID: 19262 | 基因类型: protein coding

关于 Ptpra

功能概要

Enables protein tyrosine Phosphatase activity. Involved in integrin-mediated signaling pathway; modulation of chemical synaptic transmission; and regulation of focal adhesion assembly. Acts upstream of or within Insulin Receptor signaling pathway and protein phosphorylation. Located in focal adhesion and membrane. Is active in Schaffer collateral - CA1 synapse. Is integral component of synaptic membrane. Is expressed in several structures, including adrenal gland; central nervous system; decidua; extraembryonic component; and future brain. Orthologous to human PTPRA (protein tyrosine Phosphatase receptor type A). [provided by Alliance of Genome Resources, Apr 2022]

Ptpra 基因产物(3)

mRNA Protein Name
NM_001163688.1 NP_001157160.1 receptor-type tyrosine-protein phosphatase alpha isoform 2 precursor
NM_001355161.1 NP_001342090.1 receptor-type tyrosine-protein phosphatase alpha isoform 3 precursor
NM_008980.2 NP_033006.2 receptor-type tyrosine-protein phosphatase alpha isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
7518772 MGI
enables protein tyrosine phosphatase activity IMP
IMP: 通过突变表型推断
22801373 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within insulin receptor signaling pathway IMP
IMP: 通过突变表型推断
14733908 MGI
involved in integrin-mediated signaling pathway IMP
IMP: 通过突变表型推断
22801373 MGI
involved in modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
12912911 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
12912911 MGI
acts upstream of or within protein phosphorylation IDA
IDA: 通过直接分析推断
14733908 MGI
involved in regulation of focal adhesion assembly IMP
IMP: 通过突变表型推断
22801373 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
12912911 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: 通过突变表型推断
12912911 MGI
located in focal adhesion IMP
IMP: 通过突变表型推断
22801373 MGI
located in membrane IMP
IMP: 通过突变表型推断
22801373 MGI
is active in synaptic membrane IDA
IDA: 通过直接分析推断
16899073 MGI
is active in synaptic membrane IEP
IEP: 通过表达模式推断
16899073 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

receptor-type tyrosine-protein phosphatase alpha

LCA-related phosphatase

PTPTY-28

R-PTP-alpha

protein-tyrosine phosphatase alpha

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11432 PTPRA Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19478 Ptpra Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25971 Ptpra Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptpra NCBI NCBI:5786
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