1. Gene
  2. Ptpre - protein tyrosine phosphatase, receptor type, E Gene

Ptpre - protein tyrosine phosphatase, receptor type, E Gene

种属: Mus musculus

同用名: PTPe; PTPepsilon; RPTPepsilon

基因 ID: 19267 | 基因类型: protein coding

关于 Ptpre

功能概要

Enables identical protein binding activity and protein tyrosine Phosphatase activity. Involved in negative regulation of Insulin Receptor signaling pathway and regulation of mast cell activation. Acts upstream of or within transmembrane receptor protein tyrosine Phosphatase signaling pathway. Located in cytoplasm and plasma membrane. Is expressed in midbrain and superior colliculus. Orthologous to human PTPRE (protein tyrosine Phosphatase receptor type E). [provided by Alliance of Genome Resources, Apr 2022]

Ptpre 基因产物(5)

mRNA Protein Name
NM_001316678.1 NP_001303607.1 receptor-type tyrosine-protein phosphatase epsilon isoform a
NM_001316679.1 NP_001303608.1 receptor-type tyrosine-protein phosphatase epsilon isoform b precursor
NM_001316680.1 NP_001303609.1 receptor-type tyrosine-protein phosphatase epsilon isoform c precursor
NM_001316681.1 NP_001303610.1 receptor-type tyrosine-protein phosphatase epsilon isoform d
NM_011212.3 NP_035342.3 receptor-type tyrosine-protein phosphatase epsilon isoform b precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
12861030 MGI
enables protein tyrosine phosphatase activity IDA
IDA: 通过直接分析推断
12861030 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cell surface receptor protein tyrosine phosphatase signaling pathway IDA
IDA: 通过直接分析推断
12861030 MGI
involved in negative regulation of insulin receptor signaling pathway IDA
IDA: 通过直接分析推断
18006633 MGI
involved in regulation of mast cell activation IMP
IMP: 通过突变表型推断
19508371 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
18006633 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
18006633 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

receptor-type tyrosine-protein phosphatase epsilon

R-PTP-epsilon

protein-tyrosine phosphatase epsilon

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptpre NCBI NCBI:5791