2. Gene
  3. Upf1 - UPF1 regulator of nonsense transcripts homolog (yeast) Gene

Upf1 - UPF1 regulator of nonsense transcripts homolog (yeast) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: NORF1; Rent1; Upflp; PNORF-1; B430202H16Rik

基因 ID: 19704 | 基因类型: protein coding

关于 Upf1

功能概要

Predicted to enable RNA helicase activity; chromatin binding activity; and nucleic acid binding activity. Acts upstream of or within dosage compensation by inactivation of X chromosome. Predicted to be located in chromatin; chromosome, telomeric region; and nucleoplasm. Predicted to be part of exon-exon junction complex and supraspliceosomal complex. Predicted to be active in cytoplasm. Is expressed in cerebral cortex ventricular layer; embryo; and oocyte. Orthologous to human UPF1 (UPF1 RNA helicase and ATPase). [provided by Alliance of Genome Resources, Apr 2022]

Upf1 基因产物(2)

mRNA Protein Name
NM_001122829.2 NP_001116301.1 regulator of nonsense transcripts 1 isoform a
NM_030680.3 NP_109605.2 regulator of nonsense transcripts 1 isoform b
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
23202588 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within positive regulation of mRNA cis splicing, via spliceosome IMP
IMP: 通过突变表型推断
16789828 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

regulator of nonsense transcripts 1

ATP-dependent helicase RENT1

regulator of nonsense transcripts 1 (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog)

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-111374 NMDI14 Modulator 99.68% 否
HY-124719 hSMG-1 inhibitor 11j Inhibitor 99.82% 否
HY-RS15482 UPF1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24987 Upf1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18505 Upf1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Upf1 NCBI NCBI:5976
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