Pde2a - phosphodiesterase 2A, cGMP-stimulated Gene

中文名称：磷酸二酯酶 2A，cGMP 刺激

种属: Mus musculus

同用名: cGSPDE; CGS-PDE

关于 Pde2a

功能概要

该基因编码的蛋白可启动多种功能，包括 3',5'-环状核苷酸磷酸二酯酶活性； GAF域绑定活动；和环核苷酸结合活性。涉及多个过程，包括cGMP分解代谢过程；环核苷酸介导的信号；和细胞内信号转导的负调节。作用于脂多糖细胞反应的上游或内部；循环系统发育；和调节一氧化氮介导的信号转导。位于几种细胞成分中，包括线粒体；细胞质的核周区；和突触前膜。以多种结构表达，包括泌尿生殖系统；直觉;淋巴系统；神经系统;和感觉器官。与人 PDE2A（磷酸二酯酶 2A）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables several functions, including 3',5'-cyclic-nucleotide phosphodiesterase activity; GAF domain binding activity; and cyclic nucleotide binding activity. Involved in several processes, including cGMP catabolic process; cyclic-nucleotide-mediated signaling; and negative regulation of intracellular signal transduction. Acts upstream of or within cellular response to lipopolysaccharide; circulatory system development; and regulation of nitric oxide mediated signal transduction. Located in several cellular components, including mitochondrion; perinuclear region of cytoplasm; and presynaptic membrane. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system; nervous system; and sensory organ. Orthologous to human PDE2A (phosphodiesterase 2A). [provided by Alliance of Genome Resources, Apr 2022]