1. Gene
  2. Adgrg6 - adhesion G protein-coupled receptor G6 Gene

Adgrg6 - adhesion G protein-coupled receptor G6 Gene

种属: Mus musculus

同用名: DREG; Gm222; Gpr126; 1190004A11Rik

基因 ID: 215798 | 基因类型: protein coding

关于 Adgrg6

功能概要

Enables laminin binding activity. Involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; heart trabecula formation; and myelination in peripheral nervous system. Predicted to be located in cell surface; cytoplasm; and plasma membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including heart; lung; otocyst; paraxial mesenchyme; and spleen. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome. Orthologous to human ADGRG6 (adhesion G protein-coupled receptor G6). [provided by Alliance of Genome Resources, Apr 2022]

Adgrg6 基因产物(1)

mRNA Protein Name
NM_001002268.3 NP_001002268.1 adhesion G-protein coupled receptor G6 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables laminin binding IMP
IMP: 通过突变表型推断
25695270 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
27501152 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
27501152 MGI
involved in heart trabecula formation IMP
IMP: 通过突变表型推断
24082093 MGI
involved in mitochondrion organization IMP
IMP: 通过突变表型推断
24082093 MGI
involved in myelination in peripheral nervous system IMP
IMP: 通过突变表型推断
24227709 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

adhesion G-protein coupled receptor G6

G protein coupled receptor Gpr126

G-protein coupled receptor 126

developmentally regulated G-protein-coupled receptor

probable G-protein coupled receptor 126

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adgrg6 NCBI NCBI:57211