2. Gene
  3. Tead2 - TEA domain family member 2 Gene

Tead2 - TEA domain family member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: ETF; Etdf; TEF4; TEF-4; ETEF-1; TEAD-2

基因 ID: 21677 | 基因类型: protein coding

关于 Tead2

功能概要

Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of cell death. Acts upstream of or within several processes, including cellular response to retinoic acid; mesenchyme development; and tube morphogenesis. Part of transcription regulator complex. Is expressed in several structures, including branchial arch; central nervous system; early conceptus; genitourinary system; and limb bud. Orthologous to human TEAD2 (TEA domain transcription factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Tead2 基因产物(5)

mRNA Protein Name
NM_001285498.2 NP_001272427.1 transcriptional enhancer factor TEF-4 isoform a
NM_001285500.2 NP_001272429.1 transcriptional enhancer factor TEF-4 isoform b
NM_001379272.1 NP_001366201.1 transcriptional enhancer factor TEF-4 isoform a
NM_001379273.1 NP_001366202.1 transcriptional enhancer factor TEF-4 isoform a
NM_011565.3 NP_035695.1 transcriptional enhancer factor TEF-4 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
7629195 MGI
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
14736747 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
16207754 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
10934189 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to retinoic acid IDA
IDA: 通过直接分析推断
21385842 MGI
acts upstream of or within embryonic heart tube morphogenesis IGI
IGI: 通过遗传相互作用推断
18332127 MGI
acts upstream of or within lateral mesoderm development IGI
IGI: 通过遗传相互作用推断
18332127 MGI
involved in mesenchyme development IGI
IGI: 通过遗传相互作用推断
20596238 MGI
involved in nervous system development IGI
IGI: 通过遗传相互作用推断
20596238 MGI
acts upstream of or within neural tube closure IMP
IMP: 通过突变表型推断
17868131 MGI
acts upstream of or within notochord development IGI
IGI: 通过遗传相互作用推断
18332127 MGI
acts upstream of or within paraxial mesoderm development IGI
IGI: 通过遗传相互作用推断
18332127 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
9502435 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
16207754 MGI
acts upstream of or within regulation of stem cell differentiation IMP
IMP: 通过突变表型推断
21385842 MGI
acts upstream of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
14736747 MGI
acts upstream of or within vasculogenesis IGI
IGI: 通过遗传相互作用推断
18332127 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of transcription regulator complex IDA
IDA: 通过直接分析推断
16207754 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcriptional enhancer factor TEF-4

embryonic TEA domain-containing factor

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B1221 Flufenamic acid 99.93% 否
Pre-clinical Phase
生物活性分子 (12)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-139330 MGH-CP1 Inducer 99.56% 否
HY-147135 MYF-03-69 98.11% 否
HY-172113 H122 98.04% 否
HY-158342 PROTAC TEAD degrader-1 Degrader 99.82% 否
HY-B1221S1 Flufenamic acid-13C6 99.5% 否
HY-161569 TEAD-IN-11 Inhibitor 99.82% 否
HY-161568 TEAD-IN-10 Inhibitor / 否
HY-173139 TEAD-IN-19 Inhibitor / 否
HY-B1221S Flufenamic acid-d4 / 否
HY-RS14343 TEAD2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19240 Tead2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25729 Tead2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tead2 NCBI NCBI:8463
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