1. Gene
  2. Usp5 - ubiquitin specific peptidase 5 (isopeptidase T) Gene

Usp5 - ubiquitin specific peptidase 5 (isopeptidase T) Gene

种属: Mus musculus

同用名: ISOT; Ucht; ISOT-1

基因 ID: 22225 | 基因类型: protein coding

关于 Usp5

功能概要

Predicted to enable cysteine-type endopeptidase activity; thiol-dependent deubiquitinase; and ubiquitin binding activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process and protein K48-linked deubiquitination. Predicted to act upstream of or within proteolysis. Predicted to be active in cytosol and nucleus. Orthologous to human USP5 (ubiquitin specific peptidase 5). [provided by Alliance of Genome Resources, Apr 2022]

Usp5 基因产物(9)

mRNA Protein Name
NM_001326594.2 NP_001313523.1 ubiquitin carboxyl-terminal hydrolase 5 isoform 2
NM_001410487.1 NP_001397416.1 ubiquitin carboxyl-terminal hydrolase 5 isoform 3
NM_001410488.1 NP_001397417.1 ubiquitin carboxyl-terminal hydrolase 5 isoform 4
NM_001410489.1 NP_001397418.1 ubiquitin carboxyl-terminal hydrolase 5 isoform 5
NM_001410490.1 NP_001397419.1 ubiquitin carboxyl-terminal hydrolase 5 isoform 5
NM_001410491.1 NP_001397420.1 ubiquitin carboxyl-terminal hydrolase 5 isoform 6
NM_001410492.1 NP_001397421.1 ubiquitin carboxyl-terminal hydrolase 5 isoform 6
NM_001410493.1 NP_001397422.1 ubiquitin carboxyl-terminal hydrolase 5 isoform 6
NM_013700.3 NP_038728.1 ubiquitin carboxyl-terminal hydrolase 5 isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19156909 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation protein catabolic process at presynapse EXP
EXP: 通过实验结果推断
25189210 MGI
involved in regulation protein catabolic process at presynapse IDA
IDA: 通过直接分析推断
25189210 MGI
involved in regulation protein catabolic process at presynapse IEP
IEP: 通过表达模式推断
25189210 MGI
involved in regulation protein catabolic process at presynapse IMP
IMP: 通过突变表型推断
25189210 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ubiquitin carboxyl-terminal hydrolase 5

deubiquitinating enzyme 5

isopeptidase T

ubiquitin carboxy terminal hydrolase T

ubiquitin specific protease 5

ubiquitin thioesterase 5

ubiquitin thiolesterase 5

ubiquitin-specific-processing protease 5

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Usp5 NCBI NCBI:8078