2. Gene
  3. Senp1 - SUMO1/sentrin specific peptidase 1 Gene

Senp1 - SUMO1/sentrin specific peptidase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: suPr-2; D15Ertd528e; 2310046A20Rik; E330036L07Rik

基因 ID: 223870 | 基因类型: protein coding

关于 Senp1

功能概要

Enables SUMO-specific isopeptidase activity. Acts upstream of or within negative regulation of proteasomal ubiquitin-dependent protein catabolic process; protein desumoylation; and regulation of definitive erythrocyte differentiation. Predicted to be located in focal adhesion; nuclear membrane; and nucleoplasm. Predicted to be active in nucleus. Is expressed in embryo and heart. Used to study type 1 diabetes mellitus. Orthologous to human SENP1 (SUMO specific peptidase 1). [provided by Alliance of Genome Resources, Apr 2022]

Senp1 基因产物(2)

mRNA Protein Name
NM_001379573.1 NP_001366502.1 sentrin-specific protease 1 isoform 1
NM_144851.5 NP_659100.1 sentrin-specific protease 1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables deSUMOylase activity IDA
IDA: 通过直接分析推断
22942423 MGI
enables deSUMOylase activity IMP
IMP: 通过突变表型推断
20233849 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
22942423 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of proteasomal ubiquitin-dependent protein catabolic process IMP
IMP: 通过突变表型推断
17981124 MGI
acts upstream of proteasome-mediated ubiquitin-dependent protein catabolic process IMP
IMP: 通过突变表型推断
17981124 MGI
acts upstream of or within protein desumoylation IDA
IDA: 通过直接分析推断
15767674 MGI
involved in protein desumoylation IDA
IDA: 通过直接分析推断
20233849 MGI
acts upstream of or within protein desumoylation IMP
IMP: 通过突变表型推断
15923632 MGI
acts upstream of or within regulation of definitive erythrocyte differentiation IMP
IMP: 通过突变表型推断
17981124 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in postsynaptic cytosol IDA
IDA: 通过直接分析推断
33113832 MGI
is active in presynaptic cytosol IDA
IDA: 通过直接分析推断
33113832 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

sentrin-specific protease 1

SUMO-1 protease 2

SUMO1/sentrin specific protease 1

sentrin/SUMO-specific protease SENP1

相关产品

Pre-clinical Phase
生物活性分子 (13)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N0330 Momordin Ic 99.78% 否
HY-N2360 Hinokiflavone 99.81% 否
HY-103435 Vialinin A 99.90% 否
HY-124586 Streptonigrin 99.20% 否
HY-134596 SENP1-IN-3 Inhibitor 99.92% 否
HY-134594 SENP1-IN-1 Inhibitor 99.55% 否
HY-151358 SENP2-IN-1 Inhibitor 98.05% 否
HY-134597 SENP1-IN-4 Inhibitor 98.0% 否
HY-134595 SENP1-IN-2 Inhibitor / 否
HY-RS12671 SENP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W342380 SPI-05 Inhibitor / 否
HY-RS16839 Senp1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23281 Senp1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Senp1 NCBI NCBI:29843
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