1. Metabolic Enzyme/Protease
  2. E1/E2/E3 Enzyme
  3. SPI-05

SPI-05 (NSC 5067) 是一种非竞争性的 SUMO 特异性蛋白酶 (SENP1/2) 抑制剂 (IC50=60 μM)。SPI-05 有望用于癌症的研究,如 SENP1 过表达的前列腺癌和缺氧驱动的实体瘤。

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SPI-05

SPI-05 Chemical Structure

CAS No. : 5463-64-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SPI-05 (NSC 5067) is a non-competitive SUMO-specific proteases (SENP1/2) inhibitor (IC50=60 μM). SPI-05 is promising for research of cancers, such as prostate cancer and hypoxia-driven solid tumors with SENP1 overexpression[1].

分子量

678.74

Formula

C34H26N6O6S2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
SPI-05
目录号:
HY-W342380
需求量: