1. Gene
  2. Wnt2 - wingless-type MMTV integration site family, member 2 Gene

Wnt2 - wingless-type MMTV integration site family, member 2 Gene

种属: Mus musculus

同用名: Irp; Mirp; Wnt-2; Wnt2a; Int1l1; 2610510E18Rik

基因 ID: 22413 | 基因类型: protein coding

关于 Wnt2

功能概要

Predicted to enable cytokine activity and Frizzled binding activity. Involved in cell proliferation in midbrain and positive regulation of neurogenesis. Acts upstream of or within several processes, including circulatory system development; lung induction; and positive regulation of cell population proliferation. Predicted to be located in collagen-containing extracellular matrix and cytoplasm. Predicted to be extrinsic component of external side of plasma membrane. Predicted to be active in extracellular space. Is expressed in several structures, including embryo mesenchyme; face; heart and pericardium; reproductive system; and urethra. Human ortholog(s) of this gene implicated in breast carcinoma; hepatocellular carcinoma; and urinary system Cancer. Orthologous to human WNT2 (Wnt family member 2). [provided by Alliance of Genome Resources, Apr 2022]

Wnt2 基因产物(1)

mRNA Protein Name
NM_023653.5 NP_076142.3 protein Wnt-2 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Wnt signaling pathway IGI
IGI: 通过遗传相互作用推断
11092808 MGI
acts upstream of or within atrial cardiac muscle tissue morphogenesis IMP
IMP: 通过突变表型推断
20159597 MGI
acts upstream of or within canonical Wnt signaling pathway IDA
IDA: 通过直接分析推断
9652750 MGI
acts upstream of or within canonical Wnt signaling pathway IGI
IGI: 通过遗传相互作用推断
19686689 MGI
acts upstream of or within canonical Wnt signaling pathway IMP
IMP: 通过突变表型推断
20159597 MGI
acts upstream of or within cardiac epithelial to mesenchymal transition IMP
IMP: 通过突变表型推断
20159597 MGI
acts upstream of cardiac muscle cell proliferation IMP
IMP: 通过突变表型推断
20159597 MGI
involved in cell proliferation in midbrain IMP
IMP: 通过突变表型推断
20018874 MGI
acts upstream of epithelial cell proliferation IMP
IMP: 通过突变表型推断
19686689 MGI
acts upstream of epithelial cell proliferation involved in lung morphogenesis IMP
IMP: 通过突变表型推断
19686689 MGI
acts upstream of or within labyrinthine layer blood vessel development IMP
IMP: 通过突变表型推断
8951051 MGI
acts upstream of or within lung induction IGI
IGI: 通过遗传相互作用推断
19686689 MGI
acts upstream of mesenchymal cell proliferation IMP
IMP: 通过突变表型推断
19686689 MGI
acts upstream of or within positive regulation of cardiac muscle cell proliferation IMP
IMP: 通过突变表型推断
20159597 MGI
acts upstream of or within positive regulation of epithelial cell proliferation IMP
IMP: 通过突变表型推断
19686689 MGI
acts upstream of or within positive regulation of epithelial cell proliferation involved in lung morphogenesis IMP
IMP: 通过突变表型推断
19686689 MGI
acts upstream of or within positive regulation of mesenchymal cell proliferation IMP
IMP: 通过突变表型推断
19686689 MGI
involved in positive regulation of neurogenesis IDA
IDA: 通过直接分析推断
20018874 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
20159597 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

protein Wnt-2

INT-1-related protein

wingless-related MMTV integration site 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Wnt2 NCBI NCBI:7472