2. Gene
  3. Wnt3 - wingless-type MMTV integration site family, member 3 Gene

Wnt3 - wingless-type MMTV integration site family, member 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Int-4; Wnt-3

基因 ID: 22415 | 基因类型: protein coding

关于 Wnt3

功能概要

Enables protein domain specific binding activity. Involved in positive regulation of Wnt signaling pathway. Acts upstream of or within several processes, including axis specification; embryonic morphogenesis; and generation of neurons. Located in extracellular matrix. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; embryo ectoderm; and genitourinary system. Human ortholog(s) of this gene implicated in tetraamelia syndrome 1. Orthologous to human WNT3 (Wnt family member 3). [provided by Alliance of Genome Resources, Apr 2022]

Wnt3 基因产物(1)

mRNA Protein Name
NM_009521.3 NP_033547.1 proto-oncogene Wnt-3 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10866835 MGI
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
19000841 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Spemann organizer formation at the anterior end of the primitive streak IMP
IMP: 通过突变表型推断
10431240 MGI
acts upstream of or within anatomical structure formation involved in morphogenesis IMP
IMP: 通过突变表型推断
10431240 MGI
acts upstream of or within anterior/posterior axis specification IMP
IMP: 通过突变表型推断
18028899 MGI
acts upstream of or within anterior/posterior pattern specification IMP
IMP: 通过突变表型推断
10431240 MGI
acts upstream of or within axon guidance IDA
IDA: 通过直接分析推断
18716223 MGI
acts upstream of or within canonical Wnt signaling pathway IGI
IGI: 通过遗传相互作用推断
18403408 MGI
acts upstream of or within dorsal/ventral axis specification IMP
IMP: 通过突变表型推断
12569130 MGI
acts upstream of or within embryonic forelimb morphogenesis IMP
IMP: 通过突变表型推断
12569130 MGI
acts upstream of or within embryonic hindlimb morphogenesis IMP
IMP: 通过突变表型推断
12569130 MGI
acts upstream of or within gamete generation IGI
IGI: 通过遗传相互作用推断
23469192 MGI
acts upstream of gene expression IDA
IDA: 通过直接分析推断
19690384 MGI
acts upstream of or within head morphogenesis IGI
IGI: 通过遗传相互作用推断
18403408 MGI
acts upstream of or within limb development IMP
IMP: 通过突变表型推断
12569130 MGI
acts upstream of or within mesoderm formation IMP
IMP: 通过突变表型推断
10431240 MGI
acts upstream of or within negative regulation of axon extension involved in axon guidance IDA
IDA: 通过直接分析推断
18716223 MGI
involved in positive regulation of Wnt signaling pathway IDA
IDA: 通过直接分析推断
23324743 MGI
acts upstream of or within positive regulation of collateral sprouting in absence of injury IDA
IDA: 通过直接分析推断
18716223 MGI
acts upstream of or within positive regulation of gene expression IDA
IDA: 通过直接分析推断
19690384 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular matrix IDA
IDA: 通过直接分析推断
8167409 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

proto-oncogene Wnt-3

proto-oncogene Int-4

proto-oncogene protein Wnt-3

wingless-related MMTV integration site 3

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-122832 ABC99 Inhibitor 98.48% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Wnt3 NCBI NCBI:7473
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