Atf6 - activating transcription factor 6 Gene

中文名称：激活转录因子 6

种属: Mus musculus

同用名: ESTM49; Atf6alpha; 9630036G24; 9130025P16Rik

关于 Atf6

功能概要

预计该基因编码的蛋白可启动多种功能，包括 DNA 结合转录激活剂活性、RNA 聚合酶 II 特异性；蛋白质异二聚化活性；和泛素蛋白连接酶结合活性。在 RNA 聚合酶 II 的转录正调控上游或正调控内起作用。位于核内。以多种结构表达，包括胚胎间充质；眼睛;肝;长骨;和牙齿。该基因的人类直系同源物与全色盲 7 相关。与人类 ATF6（激活转录因子 6）直系同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; protein heterodimerization activity; and ubiquitin protein Ligase binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including embryo mesenchyme; eye; liver; long bone; and tooth. Human ortholog(s) of this gene implicated in achromatopsia 7. Orthologous to human ATF6 (activating transcription factor 6). [provided by Alliance of Genome Resources, Apr 2022]