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  3. Pias3 - protein inhibitor of activated STAT 3 Gene

Pias3 - protein inhibitor of activated STAT 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Pias3l

基因 ID: 229615 | 基因类型: protein coding

关于 Pias3

功能概要

Enables SUMO transferase activity. Acts upstream of or within several processes, including TNFSF11-mediated signaling pathway; negative regulation of macromolecule metabolic process; and negative regulation of osteoclast differentiation. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; eye; genitourinary system; and maxillary process. Orthologous to human PIAS3 (protein inhibitor of activated STAT 3). [provided by Alliance of Genome Resources, Apr 2022]

Pias3 基因产物(3)

mRNA Protein Name
NM_001165949.1 NP_001159421.1 E3 SUMO-protein ligase PIAS3 isoform 3
NM_018812.2 NP_061282.2 E3 SUMO-protein ligase PIAS3 isoform 2
NM_146135.2 NP_666247.1 E3 SUMO-protein ligase PIAS3 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables SUMO transferase activity IDA
IDA: 通过直接分析推断
15767674 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11060035 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
17442941 MGI
acts upstream of or within negative regulation of gene expression IDA
IDA: 通过直接分析推断
17442941 MGI
acts upstream of or within negative regulation of osteoclast differentiation IDA
IDA: 通过直接分析推断
17442941 MGI
acts upstream of or within negative regulation of osteoclast differentiation IMP
IMP: 通过突变表型推断
17442941 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
17442941 MGI
acts upstream of or within protein sumoylation IDA
IDA: 通过直接分析推断
15767674 MGI
acts upstream of or within regulation of tumor necrosis factor-mediated signaling pathway IDA
IDA: 通过直接分析推断
17442941 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
21812053 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
34459572 MGI
located in nucleus IDA
IDA: 通过直接分析推断
14596924 MGI
is active in postsynaptic cytosol IDA
IDA: 通过直接分析推断
34459572 MGI
is active in presynaptic cytosol IDA
IDA: 通过直接分析推断
34459572 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

E3 SUMO-protein ligase PIAS3

E3 SUMO-protein transferase PIAS3

protein inhibitor of activated STAT protein 3

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10475 PIAS3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21688 Pias3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28206 Pias3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pias3 NCBI NCBI:10401
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