2. Gene
  3. Insig1 - insulin induced gene 1 Gene

Insig1 - insulin induced gene 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Insig-1; 1810013C12Rik

基因 ID: 231070 | 基因类型: protein coding

关于 Insig1

功能概要

Predicted to enable oxysterol binding activity. Acts upstream of or within several processes, including ear morphogenesis; negative regulation of fat cell differentiation; and negative regulation of lipid biosynthetic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of SREBP-SCAP-Insig complex. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including alimentary system; ganglia; neural retina; telencephalon ventricular layer; and vibrissa. Orthologous to human INSIG1 (Insulin induced gene 1). [provided by Alliance of Genome Resources, Apr 2022]

Insig1 基因产物(1)

mRNA Protein Name
NM_153526.5 NP_705746.1 insulin-induced gene 1 protein
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12242332 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cholesterol biosynthetic process IGI
IGI: 通过遗传相互作用推断
16955138 MGI
acts upstream of or within cholesterol metabolic process IGI
IGI: 通过遗传相互作用推断
16100574 MGI
acts upstream of or within cranial suture morphogenesis IGI
IGI: 通过遗传相互作用推断
16955138 MGI
acts upstream of or within inner ear morphogenesis IGI
IGI: 通过遗传相互作用推断
16955138 MGI
acts upstream of or within middle ear morphogenesis IGI
IGI: 通过遗传相互作用推断
16955138 MGI
acts upstream of or within negative regulation of fat cell differentiation IDA
IDA: 通过直接分析推断
12869692 MGI
acts upstream of or within negative regulation of fatty acid biosynthetic process IGI
IGI: 通过遗传相互作用推断
16100574 MGI
acts upstream of or within negative regulation of steroid biosynthetic process IGI
IGI: 通过遗传相互作用推断
16100574 MGI
acts upstream of or within response to sterol depletion IDA
IDA: 通过直接分析推断
12242332 MGI
acts upstream of or within roof of mouth development IGI
IGI: 通过遗传相互作用推断
16955138 MGI
acts upstream of or within sterol biosynthetic process IGI
IGI: 通过遗传相互作用推断
16955138 MGI
acts upstream of or within triglyceride metabolic process IGI
IGI: 通过遗传相互作用推断
16100574 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

insulin-induced gene 1 protein

INSIG-1 membrane protein

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-121012 (rac)-AG-205 / 否
HY-RS06837 INSIG1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17851 Insig1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24319 Insig1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Insig1 NCBI NCBI:3638
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