1. Gene
  2. Smyd5 - SET and MYND domain containing 5 Gene

Smyd5 - SET and MYND domain containing 5 Gene

种属: Mus musculus

同用名: Rrg1; Rai15; NN8-4AG

基因 ID: 232187 | 基因类型: protein coding

关于 Smyd5

功能概要

Enables Histone Methyltransferase activity (H4-K20 specific). Involved in several processes, including histone H4-K20 trimethylation; negative regulation of gene expression, epigenetic; and negative regulation of transposition. Is expressed in several structures, including alimentary system; brain; heart; skeletal musculature; and spleen. Orthologous to human SMYD5 (SMYD family member 5). [provided by Alliance of Genome Resources, Apr 2022]

Smyd5 基因产物(1)

mRNA Protein Name
NM_144918.2 NP_659167.2 histone-lysine N-trimethyltransferase SMYD5
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone H4K20 methyltransferase activity IMP
IMP: 通过突变表型推断
22921934 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
28250819 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of gene expression, epigenetic IMP
IMP: 通过突变表型推断
22921934 MGI
involved in regulation of stem cell differentiation IMP
IMP: 通过突变表型推断
28250819 MGI
involved in regulation of stem cell division IMP
IMP: 通过突变表型推断
28250819 MGI
involved in retrotransposon silencing by heterochromatin formation IMP
IMP: 通过突变表型推断
28951459 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

histone-lysine N-trimethyltransferase SMYD5

SET and MYND domain-containing protein 5

[histone H4]-lysine20 N-trimethyltransferase SMYD5

retinoic acid induced 15

retinoic acid responsive gene 1

retinoic acid-induced protein 15

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Smyd5 NCBI NCBI:10322