2. Gene
  3. Nsd3 - nuclear receptor binding SET domain protein 3 Gene

Nsd3 - nuclear receptor binding SET domain protein 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: WHISTLE; Whsc1l1; 6720429E03; A530023P05

基因 ID: 234135 | 基因类型: protein coding

关于 Nsd3

功能概要

This gene encodes a member of the SET domain family of histone lysine N-methyltransferase proteins. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. It acts in opposition to the Histone Demethylase Jmjd1c. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2015]

Nsd3 基因产物(4)

mRNA Protein Name
NM_001001735.2 NP_001001735.1 histone-lysine N-methyltransferase NSD3 isoform 1
NM_001081269.2 NP_001074738.1 histone-lysine N-methyltransferase NSD3 isoform 2
NM_001308481.1 NP_001295410.1 histone-lysine N-methyltransferase NSD3 isoform 1
NM_001308482.1 NP_001295411.1 histone-lysine N-methyltransferase NSD3 isoform 3
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone H3K27 methyltransferase activity IDA
IDA: 通过直接分析推断
16682010 MGI
enables histone H3K4 methyltransferase activity IDA
IDA: 通过直接分析推断
16682010 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
16682010 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

histone-lysine N-methyltransferase NSD3

WHSC1-like protein 1

nuclear SET domain-containing protein 3

wolf-Hirschhorn syndrome candidate 1-like protein 1 homolog

相关产品

Pre-clinical Phase
生物活性分子 (15)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-114208A BI-9321 trihydrochloride Antagonist 99.83% 否
HY-114340 LEM-14 98.02% 否
HY-155815 MS9715 Inhibitor 99.48% 否
HY-162308 NSD-IN-3 98.0% 否
HY-155816 PROTAC NSD3 degrader-1 99.40% 否
HY-142095 NSD3-IN-3 Inhibitor 98.0% 否
HY-125244 LEM-14-1189 Inhibitor 99.57% 否
HY-114208 BI-9321 Antagonist / 否
HY-142093 NSD3-IN-1 Inhibitor / 否
HY-142094 NSD3-IN-2 Inhibitor / 否
HY-168920 NSD-IN-4 / 否
HY-RS09589 NSD3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-142048 BI-9466 Antagonist / 否
HY-RS17221 Nsd3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23674 Nsd3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nsd3 NCBI NCBI:54904
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