2. Gene
  3. Slc13a5 - solute carrier family 13 (sodium-dependent citrate transporter), member 5 Gene

Slc13a5 - solute carrier family 13 (sodium-dependent citrate transporter), member 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Indy; Nact; mINDY; NaC2/NaCT

基因 ID: 237831 | 基因类型: protein coding

关于 Slc13a5

功能概要

Enables citrate transmembrane transporter activity; organic acid:sodium symporter activity; and succinate transmembrane transporter activity. Involved in carboxylic acid transport and cellular response to lithium ion. Acts upstream of or within succinate transport and tricarboxylic acid transport. Predicted to be located in basolateral plasma membrane; cytosol; and nucleoplasm. Predicted to be integral component of membrane. Is expressed in forelimb and humerus cartilage condensation. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 25. Orthologous to human SLC13A5 (solute carrier family 13 member 5). [provided by Alliance of Genome Resources, Apr 2022]

Slc13a5 基因产物(3)

mRNA Protein Name
NM_001004148.5 NP_001004148.1 Na(+)/citrate cotransporter isoform 1
NM_001372402.1 NP_001359331.1 Na(+)/citrate cotransporter isoform 2
NM_001372403.1 NP_001359332.1 Na(+)/citrate cotransporter isoform 3
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables citrate transmembrane transporter activity IDA
IDA: 通过直接分析推断
14656221 MGI
enables organic acid:sodium symporter activity IDA
IDA: 通过直接分析推断
26324167 MGI
enables succinate transmembrane transporter activity IDA
IDA: 通过直接分析推断
14656221 MGI
enables tricarboxylic acid transmembrane transporter activity IDA
IDA: 通过直接分析推断
14656221 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in alpha-ketoglutarate transport IDA
IDA: 通过直接分析推断
26324167 MGI
involved in cellular response to lithium ion IDA
IDA: 通过直接分析推断
26324167 MGI
acts upstream of or within citrate transport IDA
IDA: 通过直接分析推断
14656221 MGI
involved in citrate transport IDA
IDA: 通过直接分析推断
26324167 MGI
involved in citrate transport IMP
IMP: 通过突变表型推断
32682952 MGI
involved in fumarate transport IDA
IDA: 通过直接分析推断
26324167 MGI
involved in oxaloacetate transport IDA
IDA: 通过直接分析推断
26324167 MGI
acts upstream of or within succinate transport IDA
IDA: 通过直接分析推断
14656221 MGI
involved in succinate transport IDA
IDA: 通过直接分析推断
26324167 MGI
acts upstream of or within tricarboxylic acid transport IDA
IDA: 通过直接分析推断
14656221 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

Na(+)/citrate cotransporter

solute carrier family 13 member 5

novel solute carrier family 13 (sodium-dependent dicarboxylate transporter) (Slc13a2 or 3) member

sodium-coupled citrate transporter

sodium-dependent citrate transporter

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-120669 PF-06761281 Inhibitor 99.52% 否
HY-125990 SLC13A5-IN-1 Inhibitor 98.62% 否
HY-120103 PF-06649298 Inhibitor 98.32% 否
HY-124738 BI 01383298 Inhibitor 99.30% 否
HY-158160 LBA-3 Inhibitor / 否
HY-RS13009 SLC13A5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18581 Slc13a5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25066 Slc13a5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc13a5 NCBI NCBI:284111
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