2. Gene
  3. Afp - alpha-fetoprotein Gene

Afp - alpha-fetoprotein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 24177 | 基因类型: protein coding

关于 Afp

功能概要

Predicted to enable fatty acid binding activity and zinc ion binding activity. Involved in several processes, including cellular response to retinoic acid; liver regeneration; and response to dexamethasone. Located in cytosol and extracellular space. Biomarker of hepatitis. Human ortholog(s) of this gene implicated in hepatitis C. Orthologous to human AFP (alpha fetoprotein). [provided by Alliance of Genome Resources, Apr 2022]

Afp 基因产物(1)

mRNA Protein Name
NM_012493.2 NP_036625.2 alpha-fetoprotein precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in animal organ regeneration IEP
IEP: 通过表达模式推断
17828713 RGD
involved in cellular response to retinoic acid IEP
IEP: 通过表达模式推断
7539613 RGD
involved in liver development IEP
IEP: 通过表达模式推断
16822301 RGD
involved in liver regeneration IEP
IEP: 通过表达模式推断
2460696 RGD
involved in pancreas development IEP
IEP: 通过表达模式推断
17880577 RGD
involved in response to dexamethasone IEP
IEP: 通过表达模式推断
2409527 RGD
involved in response to tetrachloromethane IEP
IEP: 通过表达模式推断
1711115 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
1711115 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

alpha-fetoprotein

alpha-1-fetoprotein

alpha-fetoglobulin

chloride intracellular channel 6

相关产品

Approval
生物活性分子 (3)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B0600 Tafluprost Control 99.69% 是
HY-B0601 Tafluprost acid 99.80% 否
HY-116733 Tafluprost ethyl ester Agonist / 否
Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-16031 AFP464 free base Inhibitor / Phase 2
Pre-clinical Phase
生物活性分子 (10)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-103469 Peroxy Orange 1 99.20% 否
HY-175606 EVT0185 Inhibitor 98.97% 否
HY-16031B AFP464 dihydrochloride Inhibitor 99.67% 否
HY-105315 AFP-07 Agonist / 否
HY-129293 AFP-07 free acid Agonist / 否
HY-160042 AFP aptamer sodium / 否
HY-RS00435 AFP Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS15031 TRIM26 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16874 Afp Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23316 Afp Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Afp NCBI NCBI:174
Canis familiaris Afp NCBI NCBI:403551
Macaca fascicularis Afp NCBI NCBI:102130105
Mus musculus Afp NCBI NCBI:11576
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