2. Gene
  3. Hspb1 - heat shock protein family B (small) member 1 Gene

Hspb1 - heat shock protein family B (small) member 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Hsp25; Hsp27

基因 ID: 24471 | 基因类型: protein coding

关于 Hspb1

功能概要

Enables ubiquitin binding activity. Involved in several processes, including cellular response to butyrate; cellular response to interleukin-11; and response to ischemia. Located in several cellular components, including myofibril; perikaryon; and postsynaptic density membrane. Part of Proteasome complex. Biomarker of Alzheimer's disease and transient cerebral ischemia. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2F; distal hereditary motor neuropathy type 2B; pancreatic cancer; and sarcoma. Orthologous to human HSPB1 (heat shock protein family B (small) member 1). [provided by Alliance of Genome Resources, Apr 2022]

Hspb1 基因产物(1)

mRNA Protein Name
NM_031970.4 NP_114176.4 heat shock protein beta-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11546764 RGD
enables ubiquitin binding IDA
IDA: 通过直接分析推断
12897149 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to butyrate IEP
IEP: 通过表达模式推断
11522747 RGD
involved in cellular response to hydrogen peroxide IEP
IEP: 通过表达模式推断
16324708 RGD
involved in cellular response to interleukin-11 IEP
IEP: 通过表达模式推断
12730876 RGD
involved in female pregnancy IEP
IEP: 通过表达模式推断
21900647 RGD
involved in negative regulation of cellular response to oxidative stress IMP
IMP: 通过突变表型推断
11522747 RGD
involved in negative regulation of regulatory T cell differentiation IMP
IMP: 通过突变表型推断
30287503 RGD
involved in positive regulation of neuron projection development IGI
IGI: 通过遗传相互作用推断
18541665 RGD
involved in response to angiotensin IEP
IEP: 通过表达模式推断
21931298 RGD
involved in response to ischemia IEP
IEP: 通过表达模式推断
10559386 RGD
involved in response to muscle stretch IEP
IEP: 通过表达模式推断
21900647 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in I band IDA
IDA: 通过直接分析推断
9396443 RGD
located in M band IDA
IDA: 通过直接分析推断
9396443 RGD
located in axon IDA
IDA: 通过直接分析推断
22617993 RGD
located in cardiac myofibril IDA
IDA: 通过直接分析推断
9396443 RGD
located in dendrite IDA
IDA: 通过直接分析推断
22617993 RGD
located in perikaryon IDA
IDA: 通过直接分析推断
22617993 RGD
located in postsynaptic density membrane IDA
IDA: 通过直接分析推断
22617993 RGD
part of proteasome complex IDA
IDA: 通过直接分析推断
12897149 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

heat shock protein beta-1

HSP 27

heat shock 27 kDa protein 1

heat shock 27kDa protein 1

heat shock protein B1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06438 HSPB1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17913 Hspb1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24382 Hspb1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hspb1 NCBI NCBI:3315
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