2. Gene
  3. Dgat2 - diacylglycerol O-acyltransferase 2 Gene

Dgat2 - diacylglycerol O-acyltransferase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: ARAT

基因 ID: 252900 | 基因类型: protein coding

关于 Dgat2

功能概要

Enables diacylglycerol O-acyltransferase activity. Involved in several processes, including bile acid signaling pathway; positive regulation of gluconeogenesis; and regulation of lipid metabolic process. Located in intracellular membrane-bounded organelle. Used to study fatty liver disease. Biomarker of chronic kidney disease; non-alcoholic fatty liver disease; and premature menopause. Human ortholog(s) of this gene implicated in non-alcoholic fatty liver disease. Orthologous to human DGAT2 (diacylglycerol O-acyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]

Dgat2 基因产物(1)

mRNA Protein Name
NM_001012345.1 NP_001012345.1 diacylglycerol O-acyltransferase 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables diacylglycerol O-acyltransferase activity IDA
IDA: 通过直接分析推断
12235188 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in diacylglycerol metabolic process IMP
IMP: 通过突变表型推断
17526931 RGD
involved in negative regulation of fatty acid oxidation IMP
IMP: 通过突变表型推断
17526931 RGD
involved in positive regulation of gluconeogenesis IMP
IMP: 通过突变表型推断
17526931 RGD
involved in positive regulation of triglyceride biosynthetic process IMP
IMP: 通过突变表型推断
17526931 RGD
involved in regulation of cholesterol metabolic process IMP
IMP: 通过突变表型推断
17526931 RGD
involved in regulation of lipoprotein metabolic process IMP
IMP: 通过突变表型推断
17526931 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
26394137 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

diacylglycerol O-acyltransferase 2

acyl-CoA retinol O-fatty-acyltransferase

diglyceride acyltransferase 2

retinol O-fatty-acyltransferase

相关产品

Pre-clinical Phase
生物活性分子 (17)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-108341A PF-06424439 methanesulfonate Inhibitor 99.85% 否
HY-32219 T863 Inhibitor 99.83% 否
HY-108341 PF-06424439 Inhibitor 99.89% 否
HY-110381 JNJ-DGAT2-A Inhibitor 98.26% 否
HY-156259 PF-07202954 Inhibitor 98.82% 否
HY-159698A IONIS-DGAT 2Rx sodium Inhibitor 96.10% 否
HY-RS03711 DGAT2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-23199 H2-003 Inhibitor 99.53% 否
HY-169499 (R)-2-(3-(2-Ethoxyphenoxy)piperidin-1-yl)pyrimidine-5-carboxylic Acid 99.9% 否
HY-118386 H2-005 / 否
HY-145624 Obeversen Inhibitor / 否
HY-145624A Obeversen sodium Inhibitor / 否
HY-159698 IONIS-DGAT 2Rx Inhibitor / 否
HY-162854 Diacylglycerol acyltransferase inhibitor-2 Inhibitor / 否
HY-162978 DGAT2-IN-3 Inhibitor / 否
HY-RS16657 Dgat2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23092 Dgat2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dgat2 NCBI NCBI:84649
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