2. Gene
  3. Map2 - microtubule-associated protein 2 Gene

Map2 - microtubule-associated protein 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: MAP2R; Mtap2

基因 ID: 25595 | 基因类型: protein coding

关于 Map2

功能概要

Enables actin binding activity; microtubule binding activity; and protein kinase binding activity. Involved in several processes, including negative regulation of cellular component organization; positive regulation of vesicle transport along microtubule; and response to progesterone. Located in several cellular components, including axon; dendrite; and endoplasmic reticulum. Part of protein-containing complex. Used to study Alzheimer's disease and cerebral infarction. Biomarker of arteriovenous malformation; asphyxia neonatorum; brain ischemia; sciatic neuropathy; and temporal lobe epilepsy. Orthologous to human MAP2 (microtubule associated protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Map2 基因产物(1)

mRNA Protein Name
NM_013066.1 NP_037198.1 microtubule-associated protein 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin binding IMP
IMP: 通过突变表型推断
11029056 RGD
enables microtubule binding IMP
IMP: 通过突变表型推断
11029056 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
15623521 RGD
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
2561973 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of axon extension IMP
IMP: 通过突变表型推断
28426968 RGD
involved in negative regulation of microtubule depolymerization IMP
IMP: 通过突变表型推断
11029056 RGD
involved in negative regulation of microtubule polymerization IMP
IMP: 通过突变表型推断
28426968 RGD
involved in positive regulation of anterograde dense core granule transport IMP
IMP: 通过突变表型推断
28426968 RGD
involved in positive regulation of anterograde synaptic vesicle transport IMP
IMP: 通过突变表型推断
28426968 RGD
involved in regulation of organelle transport along microtubule IMP
IMP: 通过突变表型推断
28426968 RGD
involved in regulation of protein localization IMP
IMP: 通过突变表型推断
28426968 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
21683086 RGD
involved in response to progesterone IEP
IEP: 通过表达模式推断
21683086 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin cytoskeleton IMP
IMP: 通过突变表型推断
11029056 RGD
located in apical distal dendrite IDA
IDA: 通过直接分析推断
3517689 RGD
located in axon hillock IDA
IDA: 通过直接分析推断
3517689 RGD
located in axon initial segment IDA
IDA: 通过直接分析推断
28426968 RGD
located in basal dendrite IDA
IDA: 通过直接分析推断
3517689 RGD
located in cytoplasm IDA
IDA: 通过直接分析推断
2509111 RGD
located in cytoplasm IMP
IMP: 通过突变表型推断
11029056 RGD
located in dendrite IDA
IDA: 通过直接分析推断
10712642 RGD
located in dendrite cytoplasm IDA
IDA: 通过直接分析推断
3517689 RGD
located in dendritic branch IDA
IDA: 通过直接分析推断
3835499 RGD
located in dendritic filopodium IDA
IDA: 通过直接分析推断
3517689 RGD
located in dendritic growth cone IDA
IDA: 通过直接分析推断
3517689 RGD
located in dendritic shaft IDA
IDA: 通过直接分析推断
3835499 RGD
located in distal dendrite IDA
IDA: 通过直接分析推断
3835499 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
2743390 RGD
NOT located in main axon IDA
IDA: 通过直接分析推断
3517689 RGD
located in microtubule cytoskeleton IMP
IMP: 通过突变表型推断
11029056 RGD
located in neuron projection IDA
IDA: 通过直接分析推断
21119615 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
3835499 RGD
is active in postsynapse IDA
IDA: 通过直接分析推断
2743390 RGD
located in primary dendrite IDA
IDA: 通过直接分析推断
3835499 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
15623521 RGD
located in proximal dendrite IDA
IDA: 通过直接分析推断
3835499 RGD
located in proximal neuron projection IDA
IDA: 通过直接分析推断
28426968 RGD
located in ruffle membrane IMP
IMP: 通过突变表型推断
11029056 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

microtubule-associated protein 2

MAP-2

microtubule-associated protein 2C

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-107116 MAP4343 99.67% Phase 2
Pre-clinical Phase
生物活性分子 (35)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-136848 SM1-71 Inhibitor 96.09% 否
HY-159190 HRX-0233 Inhibitor 98.92% 否
HY-171178 DK2403 98.24% 否
HY-RS16235 Map2k4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08350 METAP2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-D2415 BODIPY-FL staurosporine 95.4% 否
HY-107116S MAP4343-d4 / 否
HY-163880 EGFR-IN-119 Inhibitor / 否
HY-168857 GSK-3β inhibitor 24 / 否
HY-E70842 MAP2K1 L115P Recombinant Human Active Protein Kinase / 否
HY-E70843 MAP2K1 P124L Recombinant Human Active Protein Kinase / 否
HY-E70844 MAP2K2 Recombinant Human Active Protein Kinase / 否
HY-P3894 P34cdc2 Kinase Fragment Modulator / 否
HY-RS08032 MAP2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08033 MAP2K1 Human Pre-designed siRNA Set A / 否
HY-RS08034 Map2k1 Mouse Pre-designed siRNA Set A / 否
HY-RS08035 Map2k1 Rat Pre-designed siRNA Set A / 否
HY-RS08036 MAP2K2 Human Pre-designed siRNA Set A / 否
HY-RS08037 Map2k2 Mouse Pre-designed siRNA Set A / 否
HY-RS08038 Map2k2 Rat Pre-designed siRNA Set A / 否
HY-RS08039 MAP2K3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08040 MAP2K4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08041 MAP2K5 Human Pre-designed siRNA Set A / 否
HY-RS08042 Map2k5 Mouse Pre-designed siRNA Set A / 否
HY-RS08043 Map2k5 Rat Pre-designed siRNA Set A / 否
HY-RS08044 MAP2K6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08045 MAP2K7 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08160 MASP2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17292 Map2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17782 Map2k6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18959 Neu1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19790 Map2k7 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23747 Map2 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24249 Map2k6 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26286 Map2k7 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Map2 NCBI NCBI:4133
Mus musculus Map2 NCBI NCBI:17756
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