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  2. Prkar1a - protein kinase cAMP-dependent type I regulatory subunit alpha Gene

Prkar1a - protein kinase cAMP-dependent type I regulatory subunit alpha Gene

种属: Rattus norvegicus

同用名: RIIA

基因 ID: 25725 | 基因类型: protein coding

关于 Prkar1a

功能概要

Enables cAMP binding activity and cAMP-dependent protein kinase regulator activity. Involved in female meiotic nuclear division; negative regulation of meiotic nuclear division; and regulation of protein kinase activity. Located in cytoplasm. Part of cAMP-dependent protein kinase complex. Human ortholog(s) of this gene implicated in Carney complex; acrodysostosis; and primary pigmented nodular adrenocortical disease. Orthologous to human PRKAR1A (protein kinase cAMP-dependent type I regulatory subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Prkar1a 基因产物(1)

mRNA Protein Name
NM_013181.2 NP_037313.1 cAMP-dependent protein kinase type I-alpha regulatory subunit
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cAMP binding IDA
IDA: 通过直接分析推断
11907174 RGD
enables cAMP-dependent protein kinase regulator activity IDA
IDA: 通过直接分析推断
11907174 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
17610895 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in female meiotic nuclear division IEP
IEP: 通过表达模式推断
12088872 RGD
involved in negative regulation of meiotic nuclear division IEP
IEP: 通过表达模式推断
12088872 RGD
involved in regulation of protein kinase activity IDA
IDA: 通过直接分析推断
11907174 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of cAMP-dependent protein kinase complex IDA
IDA: 通过直接分析推断
11907174 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

cAMP-dependent protein kinase type I-alpha regulatory subunit

protein kinase cAMP-dependent type 1 regulatory subunit alpha

protein kinase, cAMP-dependent, regulatory subunit type I alpha

protein kinase, cAMP-dependent, regulatory, type I, alpha

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Prkar1a NCBI NCBI:5573
Mus musculus Prkar1a NCBI NCBI:19084