2. Gene
  3. Ercc1 - ERCC excision repair 1, endonuclease non-catalytic subunit Gene

Ercc1 - ERCC excision repair 1, endonuclease non-catalytic subunit Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 292673 | 基因类型: protein coding

关于 Ercc1

功能概要

Predicted to enable several functions, including DNA binding activity; TFIID-class transcription factor complex binding activity; and promoter-specific chromatin binding activity. Predicted to contribute to 3' overhang single-stranded DNA endodeoxyribonuclease activity and DNA binding activity. Involved in several processes, including response to cadmium ion; response to immobilization stress; and response to sucrose. Located in nucleus. Used to study lung carcinoma. Biomarker of alcohol use disorder. Human ortholog(s) of this gene implicated in several diseases, including bone Cancer (multiple); carcinoma (multiple); cerebrooculofacioskeletal syndrome 4; hematologic Cancer (multiple); and transient cerebral ischemia. Orthologous to human ERCC1 (ERCC excision repair 1, Endonuclease non-catalytic subunit). [provided by Alliance of Genome Resources, Apr 2022]

Ercc1 基因产物(1)

mRNA Protein Name
NM_001106228.1 NP_001099698.1 DNA excision repair protein ERCC-1
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in embryonic organ development IEP
IEP: 通过表达模式推断
11425516 RGD
involved in response to cadmium ion IEP
IEP: 通过表达模式推断
25729986 RGD
involved in response to immobilization stress IEP
IEP: 通过表达模式推断
25726146 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
14670002 RGD
involved in response to sucrose IEP
IEP: 通过表达模式推断
15145517 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

DNA excision repair protein ERCC-1

excision repair cross-complementation group 1

excision repair cross-complementing 1

excision repair cross-complementing rodent repair deficiency, complementation group 1

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-100690 NSC16168 Inhibitor 98.11% 否
HY-147356 ERCC1-XPF-IN-2 Inhibitor 98.54% 否
HY-143498 ERCC1-XPF-IN-1 Inhibitor 99.37% 否
HY-RS04478 ERCC1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-161623 ERCC1/XPA interaction inhibitor 1 Inhibitor / 否
HY-RS18274 Ercc1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24752 Ercc1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ercc1 NCBI NCBI:2067
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