1. Gene
  2. Sdhb - succinate dehydrogenase complex iron sulfur subunit B Gene

Sdhb - succinate dehydrogenase complex iron sulfur subunit B Gene

种属: Rattus norvegicus

基因 ID: 298596 | 基因类型: protein coding

关于 Sdhb

功能概要

Enables Succinate Dehydrogenase (ubiquinone) activity. Involved in respiratory electron transport chain and succinate metabolic process. Located in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in Carney-Stratakis syndrome; gastrointestinal stromal tumor; mitochondrial complex II deficiency; paraganglioma; and pheochromocytoma. Orthologous to human SDHB (Succinate Dehydrogenase complex iron sulfur subunit B). [provided by Alliance of Genome Resources, Apr 2022]

Sdhb 基因产物(1)

mRNA Protein Name
NM_001100539.1 NP_001094009.1 succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables succinate dehydrogenase (quinone) activity IMP
IMP: 通过突变表型推断
16520240 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in respiratory electron transport chain IMP
IMP: 通过突变表型推断
16520240 RGD
involved in succinate metabolic process IMP
IMP: 通过突变表型推断
16520240 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial inner membrane IDA
IDA: 通过直接分析推断
16520240 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

ip

iron-sulfur subunit of complex II

succinate dehydrogenase complex, subunit B, iron sulfur (Ip)

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sdhb NCBI NCBI:6390