1. Gene
  2. Dld - dihydrolipoamide dehydrogenase Gene

Dld - dihydrolipoamide dehydrogenase Gene

种属: Rattus norvegicus

基因 ID: 298942 | 基因类型: protein coding

关于 Dld

功能概要

This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. A similar protein in human, mouse, and pig has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In homodimeric form, the protein functions as a dehydrogenase and is found in several multi-enzyme complexes that regulate energy metabolism. However, as a monomer, the protein can function as a protease. [provided by RefSeq, Jan 2014]

Dld 基因产物(1)

mRNA Protein Name
NM_199385.2 NP_955417.1 dihydrolipoyl dehydrogenase, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables NAD binding IDA
IDA: 通过直接分析推断
3753688 RGD
enables dihydrolipoyl dehydrogenase activity IDA
IDA: 通过直接分析推断
7487891 RGD
enables flavin adenine dinucleotide binding IDA
IDA: 通过直接分析推断
3753688 RGD
enables lipoamide binding IDA
IDA: 通过直接分析推断
8981046 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in 2-oxoglutarate metabolic process IDA
IDA: 通过直接分析推断
3571202 RGD
involved in acetyl-CoA biosynthetic process from pyruvate IDA
IDA: 通过直接分析推断
7487891 RGD
involved in dihydrolipoamide metabolic process IDA
IDA: 通过直接分析推断
8981046 RGD
involved in lipoate metabolic process IDA
IDA: 通过直接分析推断
8981046 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of oxoglutarate dehydrogenase complex IDA
IDA: 通过直接分析推断
3571202 RGD
part of pyruvate dehydrogenase complex IDA
IDA: 通过直接分析推断
7487891 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

dihydrolipoyl dehydrogenase, mitochondrial

dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex)

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dld NCBI NCBI:1738