2. Gene
  3. Cyp27a1 - cytochrome P450, family 27, subfamily a, polypeptide 1 Gene

Cyp27a1 - cytochrome P450, family 27, subfamily a, polypeptide 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Cyp27; P450C27

基因 ID: 301517 | 基因类型: protein coding

关于 Cyp27a1

功能概要

Enables HSP70 protein binding activity; Cholesterol 26-hydroxylase activity; and vitamin D3 25-hydroxylase activity. Involved in Cholesterol metabolic process. Located in mitochondrial inner membrane. Biomarker of extrahepatic cholestasis. Human ortholog(s) of this gene implicated in cerebrotendinous xanthomatosis. Orthologous to human CYP27A1 (Cytochrome P450 family 27 subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]

Cyp27a1 基因产物(1)

mRNA Protein Name
NM_178847.3 NP_849178.2 sterol 26-hydroxylase, mitochondrial
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables Hsp70 protein binding IDA
IDA: 通过直接分析推断
19401463 RGD
enables cholesterol 26-hydroxylase activity IDA
IDA: 通过直接分析推断
2175615 RGD
enables vitamin D3 25-hydroxylase activity IDA
IDA: 通过直接分析推断
2175615 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cholesterol metabolic process IDA
IDA: 通过直接分析推断
2175615 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial inner membrane IDA
IDA: 通过直接分析推断
19401463 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

sterol 26-hydroxylase, mitochondrial

5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase

5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase

cytochrome P-450c27/25

cytochrome P450 27

sterol 27-hydroxylase

vitamin D(3) 25-hydroxylase

相关产品

Pre-clinical Phase
生物活性分子 (12)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-130705A Tachysterol 3 99.68% 否
HY-16670 Dafadine-A Inhibitor 98.94% 否
HY-138115 7ß,27-Dihydroxycholesterol Activator ≥99.0% 否
HY-139067 25(S)-27-Hydroxy cholesterol Activator / 否
HY-176497 GW273297X Inhibitor / 否
HY-RS03450 CYP27A1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS03451 CYP27B1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS03452 CYP27C1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16287 Cyp27b1 Mouse Pre-designed siRNA Set A / 否
HY-RS17011 Cyp27a1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23454 Cyp27a1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25766 Cyp27b1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cyp27a1 NCBI NCBI:1593
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