1. Gene
  2. Mef2a - myocyte enhancer factor 2a Gene

Mef2a - myocyte enhancer factor 2a Gene

种属: Rattus norvegicus

基因 ID: 309957 | 基因类型: protein coding

关于 Mef2a

功能概要

Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in several processes, including cellular response to calcium ion; cellular response to glucose stimulus; and dendrite morphogenesis. Located in nucleus. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human MEF2A (myocyte enhancer factor 2A). [provided by Alliance of Genome Resources, Apr 2022]

Mef2a 基因产物(1)

mRNA Protein Name
NM_001014035.2 NP_001014057.1 myocyte-specific enhancer factor 2A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
10521511 RGD
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
10521511 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to calcium ion IDA
IDA: 通过直接分析推断
10521511 RGD
involved in cellular response to glucose stimulus IEP
IEP: 通过表达模式推断
18413674 RGD
involved in dendrite morphogenesis IMP
IMP: 通过突变表型推断
16484498 RGD
involved in positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
17696759 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
10521511 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
26240138 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
17696759 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

myocyte-specific enhancer factor 2A

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mef2a NCBI NCBI:4205