2. Gene
  3. TNFAIP8L3 - TNF alpha induced protein 8 like 3 Gene

TNFAIP8L3 - TNF alpha induced protein 8 like 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：TNF α 诱导蛋白 8 样 3

种属: Homo sapiens

同用名: TIPE3

基因 ID: 388121 | 基因类型: protein coding

关于 TNFAIP8L3

Cytogenetic location: 15q21.2 Genomic coordinates (GRCh38): 15:51,056,601-51,105,276 (from NCBI)

This gene has 3 transcripts (splice variants), 208 orthologues and 3 paralogues. Broad expression in endometrium (RPKM 16.6), esophagus (RPKM 6.5) and 15 other tissues.

功能概要

预计可启用磷脂酰肌醇结合活性和磷脂酰肌醇转移活性。预计参与多个过程，包括肌醇脂质介导的信号传导；细胞内信号转导的正向调节；和磷脂酰肌醇 3-激酶活性的正调节。位于细胞质和核质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable phosphatidylinositol binding activity and phosphatidylinositol transfer activity. Predicted to be involved in several processes, including inositol lipid-mediated signaling; positive regulation of intracellular signal transduction; and positive regulation of phosphatidylinositol 3-kinase activity. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TNFAIP8L3 基因产物(2)

mRNA Protein Name
NM_001311175.2 NP_001298104.1 tumor necrosis factor alpha-induced protein 8-like protein 3 isoform 2
NM_207381.4 NP_997264.2 tumor necrosis factor alpha-induced protein 8-like protein 3 isoform 1

TNFAIP8L3 蛋白结构

DUF758

DUF758: Domain of unknown function (DUF758) (108 - 291)

  • 0
  • 100
  • 200
  • 292 a.a.
蛋白主名 其他名称

tumor necrosis factor alpha-induced protein 8-like protein 3

TNF alpha-induced protein 8-like protein 3

关联疾病

疾病名称 别名
Astigmatism
Colon Mucinous Adenocarcinoma

Colonic Mucinous Adenocarcinoma

Mucinous Adenocarcinoma Of The Colon
Hereditary Spastic Paraplegia 51

Autosomal Dominant Spastic Paraplegia 51

Cpsq4

Spastic Quadriplegic Cerebral Palsy 4

Spg51

Spastic Paraplegia 51, Autosomal Recessive
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14794 TNFAIP8L3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus TNFAIP8L3 VGNC VGNC:36160
Mus musculus TNFAIP8L3 MGD MGI:2685363
Macaca mulatta TNFAIP8L3 VGNC VGNC:79260
Rattus norvegicus TNFAIP8L3 RGD RGD:1311533
Canis familiaris TNFAIP8L3 VGNC VGNC:49759
Felis catus TNFAIP8L3 VGNC VGNC:80816
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