1. Gene
  2. SCAPER - S-phase cyclin A associated protein in the ER Gene

SCAPER - S-phase cyclin A associated protein in the ER Gene

中文名称:ER 中的 S 期细胞周期蛋白 A 相关蛋白

种属: Homo sapiens

同用名: IDDRP; ZNF291; Zfp291; MSTP063

基因 ID: 49855 | 基因类型: protein coding

关于 SCAPER

Cytogenetic location: 15q24.3 Genomic coordinates (GRCh38): 15:76,347,904-76,905,340 (from NCBI)

This gene has 23 transcripts (splice variants), 211 orthologues and is associated with 5 phenotypes. Broad expression in testis (RPKM 4.5), brain (RPKM 3.0) and 25 other tissues.

功能概要

预测具有核酸结合活性和锌离子结合活性。位于胞质溶胶和核斑点。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable nucleic acid binding activity and zinc ion binding activity. Located in cytosol and nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]

SCAPER 基因产物(6)

mRNA Protein Name
NM_001145923.2 NP_001139395.1 S phase cyclin A-associated protein in the endoplasmic reticulum isoform b
NM_001353009.2 NP_001339938.1 S phase cyclin A-associated protein in the endoplasmic reticulum isoform c
NM_001353010.2 NP_001339939.1 S phase cyclin A-associated protein in the endoplasmic reticulum isoform d
NM_001353011.2 NP_001339940.1 S phase cyclin A-associated protein in the endoplasmic reticulum isoform e
NM_001353012.2 NP_001339941.1 S phase cyclin A-associated protein in the endoplasmic reticulum isoform d
NM_020843.4 NP_065894.2 S phase cyclin A-associated protein in the endoplasmic reticulum isoform a
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17698606 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within retina development in camera-type eye IMP
IMP: 通过突变表型推断
28794130 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

SCAPER 蛋白结构

zf-met

zf-met: Zinc-finger of C2H2 type (793 - 816)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1400 a.a.
蛋白主名 其他名称

S phase cyclin A-associated protein in the endoplasmic reticulum

zinc finger protein 291

SCAPER 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SCAPER Q9BY12 CDK2 Homo sapiens P24941
Anti Tag CoIP
17698606
种属内
SCAPER Q9BY12 CDK2 Homo sapiens P24941
Anti Bait CoIP
17698606
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Intellectual Developmental Disorder And Retinitis Pigmentosa

IDDRP

Speech Disorder

Speech Disorders

Brachydactyly
Syndromic Rod-Cone Dystrophy

Syndromic Retinitis Pigmentosa

Attention Deficit-Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder

ADHD

Attention Deficit Disorder

Attention Deficit-Hyperactivity Disorder, Susceptibility To

Attention Deficit Disorder With Hyperactivity

Hyperkinetic Disorder

Hyperactivity Of Childhood

Attention-Deficit/Hyperactivity Disorder

Add

Addh

Attention Deficit

Attention Deficit Disorder Of Childhood With Hyperactivity

Attention Deficit Disorder With Hyperactivity Syndrome

Hyperkinetic Syndrome

Attention-Deficit Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type

Disturbance Of Activity And Attention

Disorder Of Activity And Attention

Adhd - [Attention Deficit Hyperactivity Disorder]

Hyperkinetic Disorders

Disorder Of Activity And Attention With Hyperkinesia

Attention Deficit Syndrome With Hyperactivity

Late-Onset Retinal Degeneration

LORD

Retinal Degeneration, Late-Onset, Autosomal Dominant

Autosomal Dominant Late-Onset Retinal Degeneration

Pigmentary Retinopathy

Retinal Degeneration, Late-Onset

Retinitis Pigmentosa

Retinitis Pigmentosa

RP

Rod-Cone Dystrophy

Autosomal Recessive Retinitis Pigmentosa

Non-Syndromic Retinitis Pigmentosa

Pericentral Pigmentary Retinopathy

Pigmentary Retinopathy

Tapetoretinal Degeneration

Rcd

Retinitis Pigmentosa Autosomal Recessive

ARRP

Retinitis Pigmentosa, Autosomal Recessive

Retinitis Pigmentosa 1

Body Mass Index Quantitative Trait Locus 11

OBESITY

Obesity, Susceptibility To

Leanness, Inherited

Obesity, Susceptibility To, Bmiq11

Obesity, Mild, Early-Onset

Obesity, Association With

Obesity, Early-Onset, Susceptibility To

Obesity, Severe

Obesity, Severe, And Type Ii Diabetes

Obesity, Late-Onset

Obesity , Susceptibility To

BMIQ11

Obesity Bmiq11

Obesity, Early-Onset

Simple Obesity Nos

Excess Fat

Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified

Adiposis

Bardet-Biedl Syndrome

Bbs

Biedl-Bardet Syndrome

Cone-Rod Dystrophy 2

Cone-Rod Dystrophy

CORD2

Cone-Rod Retinal Dystrophy

Rcrd2

Cone-Rod Retinal Dystrophy 2

Crd2

Cord

Crd

Retinal Cone-Rod Dystrophy

Cone-Rod Retinal Dystrophy-2

Retinal Cone-Rod Dystrophy 2

Tapetoretinal Degeneration

Cone-Rod Degeneration

Cone Rod Dystrophy

Dystrophy, Cone-Rod

Dystrophy, Cone-Rod, Type 2

Retinitis Pigmentosa

Retinitis Pigmentosa 2

Progressive Cone-Rod Dystrophy

Combined Oxidative Phosphorylation Deficiency 16

COXPD16

Infantile Hypertrophic Cardiomyopathy Due To Mrpl44 Deficiency

Combined Oxidative Phosphorylation Defect Type 16

Combined Oxidative Phosphorylation Deficiency, Type 16

Cardiomyopathy, Dilated, 1l

Dilated Cardiomyopathy 1l

CMD1L

Cardiomyopathy, Dilated 1l

Cardiomyopathy, Dilated, Type 1l

Blount'S Disease

Blount Disease

Tibia Vara

Osteochondrosis Deformans Tibiae

Osteochondrosis Deformans Tibiae, Familial Infantile Type

Familial Infantile Type Osteochondrosis Deformans Tibiae

Blount-Barber Syndrome

Erlacher-Blount Syndrome

Infantile Tibia Vara

Tibia Vara Blount

Blount Disease, Infantile

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus SCAPER VGNC VGNC:34321
Felis catus SCAPER VGNC VGNC:64899
Canis familiaris SCAPER VGNC VGNC:45895
Rattus norvegicus SCAPER RGD RGD:621585
Macaca mulatta SCAPER VGNC VGNC:77006
Mus musculus SCAPER MGD MGI:1925976