PIPOX - pipecolic acid and sarcosine oxidase Gene

中文名称：哌啶酸和肌氨酸氧化酶

种属: Homo sapiens

同用名: LPIPOX

基因 ID: 51268 | 基因类型: protein coding

关于 PIPOX

Cytogenetic location: 17q11.2 Genomic coordinates (GRCh38): 17:29,043,141-29,057,216 (from NCBI)

This gene has 10 transcripts (splice variants) and 203 orthologues. Biased expression in liver (RPKM 113.3) and kidney (RPKM 56.6).

功能概要

启用 L-pipecolate 氧化酶活性和肌氨酸氧化酶活性。通过 L-pipecolate 参与 L-赖氨酸分解代谢为乙酰辅酶 A 的过程。位于过氧化物酶体中。 [由基因组资源联盟提供，2022 年 4 月]

Enables L-pipecolate oxidase activity and sarcosine oxidase activity. Involved in L-lysine catabolic process to acetyl-CoA via L-pipecolate. Located in peroxisome. [provided by Alliance of Genome Resources, Apr 2022]

PIPOX 基因产物(1)

mRNA	Protein	Name
NM_016518.3	NP_057602.2	peroxisomal sarcosine oxidase

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables L-pipecolate oxidase activity	IDA IDA: 通过直接分析推断	10642506	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	21044950	GOA
enables sarcosine oxidase activity	IDA IDA: 通过直接分析推断	10642506	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in L-lysine catabolic process to acetyl-CoA via L-pipecolate	IDA IDA: 通过直接分析推断	10642506	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in peroxisome	IDA IDA: 通过直接分析推断	10642506	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PIPOX 蛋白结构

DAO

0
100
200
300
390 a.a.

蛋白主名

其他名称

peroxisomal sarcosine oxidase

L-pipecolate oxidase

PIPOX 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	PIPOX	Q9P0Z9	POT1	Homo sapiens	Q9NUX5	Pull Down	21044950
种属内	PIPOX	Q9P0Z9	POT1	Homo sapiens	Q9NUX5	BiFC	21044950

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Peroxisome Biogenesis Disorder 1b

Peroxisome Biogenesis Disorder	Infantile Refsum Disease
Infantile Phytanic Acid Storage Disease	PBD1B
Refsum Disease, Infantile	Adrenoleukodystrophy, Autosomal Neonatal
Ird	Mild Pbd-Zsd
Mild Peroxisome Biogenesis Disorder-Zellweger Spectrum Disorder	Pbd-Zsd
Peroxisome Biogenesis Disorder Spectrum	Peroxisome Biogenesis Disorder-Zellweger Spectrum Disorder
Autosomal Neonatal Adrenoleukodystrophy	Refsum Disease Infantile
Peroxisome Biogenesis Disorders	Peroxisome Biogenesis Disorder, Type 1b

Zellweger Syndrome

Cerebrohepatorenal Syndrome	Zellweger Leukodystrophy
Zs	Congenital Iron Overload
Chr	Zws
Severe Pbd-Zsd	Severe Peroxisome Biogenesis Disorder-Zellweger Spectrum Disorder

Hyperlysinemia, Type I

Hyperlysinemia	Lysine Intolerance
Alpha-Aminoadipic Semialdehyde Synthase Deficiency	Lysine:Alpha-Ketoglutarate Reductase Deficiency
L-Lysine:Nad-Oxido-Reductase Deficiency	Lysine Alpha-Ketoglutarate Reductase Deficiency
Alpha-Aminoadipic Semialdehyde Deficiency Disease	Lysine Alpha-Ketoglutarate Reductase Deficiency Disease
Saccharopinuria	Hyperlysinemia Type I
Hyperlysinemias	L-Lysine Nad-Oxido-Reductase Deficiency
Familial Hyperlysinemia	Saccharopine Dehydrogenase Deficiency Disease
Hyperlysinemia, 1	HYPLYS1
Saccharopine Dehydrogenase Deficiency

Epilepsy, Pyridoxine-Dependent

Pyridoxine-Dependent Epilepsy	PDE
Pyridoxine Dependency With Seizures	Vitamin B6-Dependent Seizures
EPD	Aasa Dehydrogenase Deficiency
Antiquitin Deficiency	Pyridoxine Dependency
Glutamate Decarboxylase Deficiency	Pyridoxine-Dependent Seizures
Deficiency Of Glutamate Decarboxylase

Glutaric Acidemia I

Glutaryl-Coa Dehydrogenase Deficiency	GA1
Glutaric Acidemia Type 1	Glutaric Aciduria 1
Glutaric Aciduria Type 1	Glutaric Acidemia Type I
Glutaric Aciduria, Type 1	Glutaric Aciduria I
Ga I	Glutaricaciduria, Type I
Glutaryl-Coenzyme A Dehydrogenase Deficiency	Glutaric Academia Type 1
Glutaric Aciduria Type I	Ga-1
Gcdh Deficiency	Ga 1
Glutaric Acidemia 1	Gcdhd
Glutaric Aciduria, Type I	Glutaricaciduria I
Ga-I	Glutaricaciduria, Type 1

Peroxisomal Biogenesis Disorder

Zellweger Spectrum Disorders	Peroxisome Biogenesis Disorder-Zellweger Syndrome Spectrum
Disorders Of Peroxisome Biogenesis	Zellweger Spectrum
Zellweger Syndrome Spectrum	Peroxisomal Biogenesis Disorders
Pbd, Zss	Pbd-Zsd
Pbd-Zss	Pbd-Zellweger Spectrum Disorder
Peroxisomal Biogenesis Disorders, Zellweger Syndrome Spectrum	Peroxisome Biogenesis Disorder
Peroxisome Biogenesis Disorder Spectrum	Peroxisome Biogenesis Disorders
Zellweger Spectrum Disorder	Hyperpipecolic Acidaemia

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS10570	PIPOX Human Pre-designed siRNA Set A	Pre-designed Set	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	PIPOX	RGD	RGD:1311347
Bos taurus	PIPOX	VGNC	VGNC:32914
Mus musculus	PIPOX	MGD	MGI:1197006
Macaca mulatta	PIPOX	VGNC	VGNC:75822
Canis familiaris	PIPOX	VGNC	VGNC:44578
Felis catus	PIPOX	VGNC	VGNC:64185

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站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

PIPOX - pipecolic acid and sarcosine oxidase Gene

关于 PIPOX

功能概要

PIPOX 基因产物(1)

PIPOX 蛋白结构

PIPOX 蛋白互作信息

关联疾病

直系同源

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PIPOX - pipecolic acid and sarcosine oxidase Gene

关于 PIPOX

功能概要

PIPOX 基因产物(1)

PIPOX 蛋白结构

PIPOX 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

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B

C

F

G

H

J

L

N

Q

S

T

X

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