2. Gene
  3. Notch3 - notch receptor 3 Gene

Notch3 - notch receptor 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 56761 | 基因类型: protein coding

关于 Notch3

功能概要

Predicted to enable enzyme binding activity; identical protein binding activity; and signaling receptor activity. Involved in several processes, including Notch signaling pathway; tissue regeneration; and wound healing. Predicted to be located in actin cytoskeleton; cytosol; and nucleoplasm. Predicted to be part of receptor complex. Predicted to be active in cell surface and plasma membrane. Human ortholog(s) of this gene implicated in CADASIL 1; infantile myofibromatosis; and lateral meningocele syndrome. Orthologous to human NOTCH3 (Notch receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Notch3 基因产物(1)

mRNA Protein Name
NM_020087.3 NP_064472.3 neurogenic locus notch homolog protein 3 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in Notch signaling pathway IDA
IDA: 通过直接分析推断
11925448 RGD
involved in regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
11971902 RGD
involved in tissue regeneration IEP
IEP: 通过表达模式推断
16118793 RGD
involved in wound healing IEP
IEP: 通过表达模式推断
11549580 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

neurogenic locus notch homolog protein 3

Notch gene homolog 3

notch 3

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-15670 BMS-906024 Inhibitor 99.91% Phase 1
HY-12860 BMS-986115 Inhibitor 99.90% Phase 1
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99320 Tarextumab Inhibitor 96.80% Phase 2
Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-15827 NSC 405020 Inhibitor 99.63% 否
HY-136522 S2116 98.05% 否
HY-RS09451 NOTCH3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-136523 S2157 98.44% 否
HY-RS17213 Notch3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23665 Notch3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Notch3 NCBI NCBI:4854
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