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  2. P2ry4 - pyrimidinergic receptor P2Y, G-protein coupled, 4 Gene

P2ry4 - pyrimidinergic receptor P2Y, G-protein coupled, 4 Gene

中文名称:嘧啶能受体 P2 Y,G 蛋白偶联,4

种属: Mus musculus

同用名: P2Y4; P2Y4R

基因 ID: 57385 | 基因类型: protein coding

关于 P2ry4

Chromosome X: 99,633,760-99,638,475 reverse strand.GRCm39:CM001013.3

This gene has 1 transcript (splice variant), 168 orthologues, 13 paralogues and is associated with 2 phenotypes. Biased expression in liver adult (RPKM 7.1), large intestine adult (RPKM 3.5) and 5 other tissues.

功能概要

该基因编码的蛋白可启动 G 蛋白偶联 UTP 受体活性。在对前列腺素 E 刺激和跨上皮氯化物转运的细胞反应的上游或细胞内起作用。预测位于顶端质膜和基底外侧质膜。在骨骼肌中表达。与人 P2RY4(嘧啶能受体 P2Y4)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables G protein-coupled UTP receptor activity. Acts upstream of or within cellular response to prostaglandin E stimulus and transepithelial chloride transport. Predicted to be located in apical plasma membrane and basolateral plasma membrane. Is expressed in skeletal muscle. Orthologous to human P2RY4 (pyrimidinergic receptor P2Y4). [provided by Alliance of Genome Resources, Apr 2022]

P2ry4 基因产物(1)

mRNA Protein Name
NM_020621.4 NP_065646.1 P2Y purinoceptor 4
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled UTP receptor activity IDA
IDA: 通过直接分析推断
11259526 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to prostaglandin E stimulus IDA
IDA: 通过直接分析推断
23479225 MGI
acts upstream of or within transepithelial chloride transport IDA
IDA: 通过直接分析推断
11259526 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

P2ry4 蛋白结构

7tmA_P2Y4

7tmA_P2Y4: cd15374 (31 - 312)

7tmA_P2Y4

7tmA_P2Y4: cd15374 (31 - 58)

7tmA_P2Y4

7tmA_P2Y4: cd15374 (65 - 90)

7tmA_P2Y4

7tmA_P2Y4: cd15374 (103 - 133)

7tmA_P2Y4

7tmA_P2Y4: cd15374 (145 - 167)

7tmA_P2Y4

7tmA_P2Y4: cd15374 (192 - 221)

7tmA_P2Y4

7tmA_P2Y4: cd15374 (233 - 263)

7tmA_P2Y4

7tmA_P2Y4: cd15374 (280 - 305)

  • 0
  • 100
  • 200
  • 300
  • 361 a.a.
蛋白主名 其他名称

P2Y purinoceptor 4

P2Y4 receptor

purinergic receptor P2Y, G-protein coupled, 4

直系同源

种属 基因名 来源 基因 ID
Homo sapiens P2ry4 NCBI NCBI:5030