2. Gene
  3. Phlpp1 - PH domain and leucine rich repeat protein phosphatase 1 Gene

Phlpp1 - PH domain and leucine rich repeat protein phosphatase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Scop; Phlpp; Plekhe1

基因 ID: 59265 | 基因类型: protein coding

关于 Phlpp1

功能概要

Enables protein serine/threonine Phosphatase activity. Involved in several processes, including hippocampus development; protein dephosphorylation; and regulation of intracellular signal transduction. Located in cytoplasm; nucleus; and plasma membrane. Orthologous to human PHLPP1 (PH domain and leucine rich repeat protein Phosphatase 1). [provided by Alliance of Genome Resources, Apr 2022]

Phlpp1 基因产物(1)

mRNA Protein Name
NM_021657.2 NP_067689.2 PH domain leucine-rich repeat protein phosphatase 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein serine/threonine phosphatase activity IDA
IDA: 通过直接分析推断
20089132 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in circadian rhythm IEP
IEP: 通过表达模式推断
10570941 RGD
involved in hippocampus development IEP
IEP: 通过表达模式推断
20819118 RGD
involved in negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: 通过突变表型推断
20819118 RGD
involved in negative regulation of protein kinase C signaling IMP
IMP: 通过突变表型推断
20819118 RGD
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: 通过突变表型推断
20819118 RGD
involved in protein dephosphorylation IDA
IDA: 通过直接分析推断
20089132 RGD
involved in protein dephosphorylation IMP
IMP: 通过突变表型推断
20819118 RGD
involved in regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
20819118 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
20819118 RGD
located in cytoplasm IMP
IMP: 通过突变表型推断
20819118 RGD
located in nuclear membrane IDA
IDA: 通过直接分析推断
20819118 RGD
located in nucleoplasm IDA
IDA: 通过直接分析推断
20819118 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
20819118 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

PH domain leucine-rich repeat protein phosphatase 1

Circadian Oscillatory Protein (SCOP)

PH domain leucine-rich repeat-containing protein phosphatase 1

PH domain-containing family E member 1

SCN circadian oscillatory protein

pleckstrin homology domain containing, family E (with leucine rich repeats) me

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-19820A NSC45586 sodium ≥98.0% 否
HY-19820 NSC45586 / 否
HY-RS10447 PHLPP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18428 Phlpp1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24909 Phlpp1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Phlpp1 NCBI NCBI:23239
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