2. Gene
  3. SPRR3 - small proline rich protein 3 Gene

SPRR3 - small proline rich protein 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：富脯氨酸的小蛋白 3

种属: Homo sapiens

基因 ID: 6707 | 基因类型: protein coding

关于 SPRR3

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:153,001,749-153,003,856 (from NCBI)

This gene has 4 transcripts (splice variants), 38 orthologues and 20 paralogues. Restricted expression toward esophagus (RPKM 6973.3).

功能概要

预测可实现结构分子活性。预计参与伤口愈合。位于高尔基体和细胞质的核周区。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable structural molecule activity. Predicted to be involved in wound healing. Located in Golgi apparatus and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

SPRR3 基因产物(2)

mRNA Protein Name
NM_001097589.2 NP_001091058.1 small proline-rich protein 3
NM_005416.3 NP_005407.1 small proline-rich protein 3
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10510474 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
19211270 GOA
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
19211270 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SPRR3 蛋白结构

Cornifin

Cornifin: Cornifin (SPRR) family (17 - 75)

Cornifin

Cornifin: Cornifin (SPRR) family (67 - 167)

  • 0
  • 100
  • 169 a.a.
蛋白主名 其他名称

small proline-rich protein 3

22 kDa pancornulin

SPRR3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SPRR3 Q9UBC9 JOSD2 Homo sapiens Q8TAC2
Anti Tag CoIP
33961781
种属内
SPRR3 Q9UBC9 JOSD2 Homo sapiens Q8TAC2
Anti Tag CoIP
28514442
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Esophageal Cancer

Esophageal Carcinoma

Carcinoma Of Esophagus

Esophageal Squamous Cell Carcinoma, Somatic

Esophageal Carcinoma, Somatic

Esophagus Cancer

Gastric Cardia Adenocarcinoma

Esophageal Neoplasms

Esophageal Cancer, Somatic

Cancer Of Esophagus

Cancer Of Oesophagus

Carcinoma Of Oesophagus

Ca Lower Third Oesophagus

Ca Middle Third Oesophagus

Malignant Neoplasm Of Distal Third Of Esophagus

Malignant Neoplasm Of Lower Third Of Oesophagus

Malignant Neoplasm Of Middle Third Of Oesophagus

Malignant Neoplasm Of Proximal Third Of Esophagus

Malignant Neoplasm Of Upper Third Esophagus

Malignant Tumor Of Abdominal Esophagus

Malignant Tumor Of Distal Third Of Esophagus

Malignant Tumor Of Proximal Third Of Esophagus

Malignant Tumor Of The Middle Third Of The Esophagus

ESCR

Aerodigestive Tract Cancer

Escc

Esophageal Squamous Cell Carcinoma

Cancer, Esophageal

Malignant Neoplasm Of Esophagus

Squamous Cell Carcinoma Of Esophagus

Malignant Neoplasm Of Middle Third Of Esophagus
Skin Disease

Skin Diseases

Genodermatosis

Abnormality Of The Skin

Skin Diseases, Genetic

Skin And Subcutaneous Tissue Disease

Dermatologic Disorders
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13718 SPRR3 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SPRR3 RGD RGD:1309589
Mus musculus SPRR3 MGD MGI:1330237
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