Parp10 - poly (ADP-ribose) polymerase family, member 10 Gene

中文名称：聚 (ADP-核糖) 聚合酶家族，成员 10

种属: Mus musculus

同用名: ARTD10; PARP-10

关于 Parp10

功能概要

预计该基因编码的蛋白可启动 K63 连接的多聚泛素修饰依赖性蛋白结合活性；戊糖基转移酶活性；和转录辅阻遏物活性。预计参与多个过程，包括 NF-kappaB 转录因子活性的负调控；大分子代谢过程的负调控；和蛋白质 ADP-核糖基化。预测作用于 DNA 修复的上游或内部。预测位于高尔基体；胞质溶胶；和核仁。预计在细胞质和细胞核中有活性。与人类 PARP10（聚（ADP-核糖）聚合酶家族成员 10）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity; pentosyltransferase activity; and transcription corepressor activity. Predicted to be involved in several processes, including negative regulation of NF-kappaB transcription factor activity; negative regulation of macromolecule metabolic process; and protein ADP-ribosylation. Predicted to act upstream of or within DNA repair. Predicted to be located in Golgi apparatus; cytosol; and nucleolus. Predicted to be active in cytoplasm and nucleus. Orthologous to human PARP10 (poly(ADP-ribose) polymerase family member 10). [provided by Alliance of Genome Resources, Apr 2022]