2. Gene
  3. Smc4 - structural maintenance of chromosomes 4 Gene

Smc4 - structural maintenance of chromosomes 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: SMC-4; Smc4l1; 2500002A22Rik

基因 ID: 70099 | 基因类型: protein coding

关于 Smc4

功能概要

Enables chromatin binding activity and single-stranded DNA binding activity. Acts upstream of or within kinetochore organization; meiotic chromosome condensation; and meiotic chromosome segregation. Located in chromosome, centromeric region. Part of condensin complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human SMC4 (structural maintenance of chromosomes 4). [provided by Alliance of Genome Resources, Apr 2022]

Smc4 基因产物(2)

mRNA Protein Name
NM_001356976.1 NP_001343905.1 structural maintenance of chromosomes protein 4 isoform 2
NM_133786.4 NP_598547.1 structural maintenance of chromosomes protein 4 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin binding IDA
IDA: 通过直接分析推断
23531880 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
20139420 MGI
enables single-stranded DNA binding IDA
IDA: 通过直接分析推断
20139420 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within kinetochore organization IMP
IMP: 通过突变表型推断
21795393 MGI
acts upstream of or within meiotic chromosome condensation IMP
IMP: 通过突变表型推断
21795393 MGI
acts upstream of or within meiotic chromosome segregation IMP
IMP: 通过突变表型推断
21795393 MGI
involved in positive regulation of chromosome segregation IMP
IMP: 通过突变表型推断
25474630 MGI
involved in positive regulation of chromosome separation IMP
IMP: 通过突变表型推断
21795393 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromosome, centromeric region IDA
IDA: 通过直接分析推断
26919979 MGI
located in condensed nuclear chromosome IDA
IDA: 通过直接分析推断
25474630 MGI
part of condensin complex IDA
IDA: 通过直接分析推断
21795393 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

structural maintenance of chromosomes protein 4

SMC protein 4

SMC4 structural maintenance of chromosomes 4-like 1

XCAP-C homolog

chromosome-associated polypeptide C

Smc4 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Smc4 Q8CG47 Yy1 Mus musculus Q00899
Anti Bait CoIP
23531880
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13420 SMC4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20820 Smc4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27334 Smc4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Smc4 NCBI NCBI:10051
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