2. Gene
  3. Dusp3 - dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) Gene

Dusp3 - dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: VHR; T-DSP11; 2210015O03Rik; 5031436O03Rik

基因 ID: 72349 | 基因类型: protein coding

关于 Dusp3

功能概要

Enables protein tyrosine/serine/threonine Phosphatase activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity; and regulation of focal adhesion assembly. Acts upstream of or within protein dephosphorylation. Predicted to be located in immunological synapse and nucleoplasm. Predicted to be active in cytosol. Is expressed in central nervous system; retina; and urinary system. Orthologous to human DUSP3 (dual specificity Phosphatase 3). [provided by Alliance of Genome Resources, Apr 2022]

Dusp3 基因产物(1)

mRNA Protein Name
NM_028207.3 NP_082483.1 dual specificity protein phosphatase 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables phosphoprotein phosphatase activity IDA
IDA: 通过直接分析推断
18035061 MGI
enables protein tyrosine/serine/threonine phosphatase activity IDA
IDA: 通过直接分析推断
11432789 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to epidermal growth factor stimulus IMP
IMP: 通过突变表型推断
28759036 MGI
involved in flagellated sperm motility IDA
IDA: 通过直接分析推断
37865089 MGI
involved in negative regulation of epidermal growth factor receptor signaling pathway IMP
IMP: 通过突变表型推断
28759036 MGI
involved in peptidyl-tyrosine dephosphorylation IMP
IMP: 通过突变表型推断
28759036 MGI
involved in peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity IMP
IMP: 通过突变表型推断
28759036 MGI
acts upstream of or within protein dephosphorylation IDA
IDA: 通过直接分析推断
18035061 MGI
involved in regulation of focal adhesion assembly IMP
IMP: 通过突变表型推断
28759036 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in axonemal microtubule doublet inner sheath IDA
IDA: 通过直接分析推断
37865089 MGI
is active in sperm flagellum IDA
IDA: 通过直接分析推断
37865089 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

dual specificity protein phosphatase 3

vaccinia H1-related phosphatase

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-135457 JMS-053 Inhibitor 98.0% 否
HY-123846 MLS-0437605 Inhibitor 99.27% 否
HY-RS04064 DUSP3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17699 Dusp3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24161 Dusp3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dusp3 NCBI NCBI:1845
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