2. Gene
  3. Syvn1 - synovial apoptosis inhibitor 1, synoviolin Gene

Syvn1 - synovial apoptosis inhibitor 1, synoviolin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Hrd1; 1200010C09Rik; D530017H19Rik

基因 ID: 74126 | 基因类型: protein coding

关于 Syvn1

功能概要

Enables ubiquitin protein Ligase activity. Involved in immature B cell differentiation; protein stabilization; and proteolysis involved in cellular protein catabolic process. Acts upstream of or within in utero embryonic development and negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway. Located in endoplasmic reticulum quality control compartment. Is expressed in rib. Orthologous to human SYVN1 (synoviolin 1). [provided by Alliance of Genome Resources, Apr 2022]

Syvn1 基因产物(2)

mRNA Protein Name
NM_001164709.1 NP_001158181.1 E3 ubiquitin-protein ligase synoviolin
NM_028769.5 NP_083045.4 E3 ubiquitin-protein ligase synoviolin
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19725872 MGI
enables ubiquitin protein ligase activity IDA
IDA: 通过直接分析推断
21911472 MGI
enables ubiquitin protein ligase activity IMP
IMP: 通过突变表型推断
29907570 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in ERAD pathway IDA
IDA: 通过直接分析推断
21454652 MGI
involved in immature B cell differentiation IMP
IMP: 通过突变表型推断
29907570 MGI
acts upstream of or within in utero embryonic development IMP
IMP: 通过突变表型推断
15611074 MGI
acts upstream of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IMP
IMP: 通过突变表型推断
15611074 MGI
acts upstream of or within negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IMP
IMP: 通过突变表型推断
15611074 MGI
involved in protein catabolic process IMP
IMP: 通过突变表型推断
20160352 MGI
involved in protein stabilization IDA
IDA: 通过直接分析推断
21454652 MGI
involved in ubiquitin-dependent protein catabolic process IDA
IDA: 通过直接分析推断
21911472 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum quality control compartment IDA
IDA: 通过直接分析推断
17707796 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

E3 ubiquitin-protein ligase synoviolin

RING-type E3 ubiquitin transferase synoviolin

synoviolin 1

Syvn1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Syvn1 Q9DBY1 Ncstn Mus musculus P57716
Anti Bait CoIP
19725872
种属内
Syvn1 Q9DBY1 Ncstn Mus musculus P57716
Anti Tag CoIP
19725872
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-135844 LS-102 Inhibitor 97.92% 否
HY-RS14127 SYVN1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18845 Syvn1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25337 Syvn1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Syvn1 NCBI NCBI:84447
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